Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.49 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | ABL1 | P00519 | 2/20 | 0.46 |
| ▸ | XDH | P47989 | 2/20 | 0.45 |
| ▸ | ULK1 | O75385 | 1/20 | 0.45 |
| ▸ | KIF11 | P52732 | 2/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 4/20 | 0.43 |
| ▸ | GABRP | O00591 | 2/20 | 0.43 |
| ▸ | GABRD | O14764 | 2/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.43 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.43 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.43 |
| ▸ | GABRE | P78334 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29619548 | 1.00 | PIM1 (0.49) | PIM1PIM3CYP1A2ABL1XDH | |
| SCHEMBL14356133 | 0.82 | KIF11 (0.43) | PIM1PIM3KIF11KDM4EALDH1A1 | |
| SCHEMBL4811157 | 0.81 | XDH (0.46) | PIM1PIM3CYP1A2ABL1XDH | |
| SCHEMBL30418722 | 0.81 | XDH (0.46) | PIM1PIM3CYP1A2ABL1XDH | |
| SCHEMBL4661897 | 0.80 | KDM4E (0.58) | CYP1A2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL3938839 | 0.79 | ALDH1A1 (0.41) | PIM1PIM3CYP1A2KDM4EALDH1A1 | |
| SCHEMBL5567512 | 0.77 | KDM4E (0.68) | CYP1A2XDHKIF11NR4A2GABRP | |
| SCHEMBL3606511 | 0.76 | RAB9A (0.50) | CYP1A2XDHULK1KIF11NR4A2 | |
| SCHEMBL30039640 | 0.75 | HRH4 (0.56) | CYP1A2XDHULK1KIF11NR4A2 | |
| SCHEMBL19331400 | 0.75 | HRH4 (0.56) | CYP1A2XDHULK1KIF11NR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114181216-A | Preparation method of 3, 6-dihydropyrrolo [3,2-e ] indole-2-methyl formate | 苏州新药篮生物医药科技有限公司 | 2022-03-15 | — | — | CN | claimed |
| CN-114181216-A | Preparation method of 3, 6-dihydropyrrolo [3,2-e ] indole-2-methyl formate | 苏州新药篮生物医药科技有限公司 | 2022-03-15 | — | — | CN | disclosed |
| EP-2121667-B1 | CHEMICAL LINKERS WITH SINGLE AMINO ACIDS AND CONJUGATES THEREOF | SQUIBB & SONS LLC (US) | 2016-06-08 | — | — | EP | disclosed |
| EP-2121667-B1 | CHEMICAL LINKERS WITH SINGLE AMINO ACIDS AND CONJUGATES THEREOF | SQUIBB & SONS LLC (US) | 2016-06-08 | — | — | EP | disclosed |
| US-8664407-B2 | Chemical linkers with single amino acids and conjugates thereof | Medarex, LLC (US) | 2014-03-04 | — | — | US | disclosed |
| US-8664407-B2 | Chemical linkers with single amino acids and conjugates thereof | Medarex, LLC (US) | 2014-03-04 | — | — | US | disclosed |
| US-8664407-B2 | Chemical linkers with single amino acids and conjugates thereof | Medarex, LLC (US) | 2014-03-04 | — | — | US | disclosed |
| US-8461117-B2 | Chemical linkers and cleavable substrates and conjugates thereof | MEDAREX, INC. (US) | 2013-06-11 | — | — | US | disclosed |
| US-8461117-B2 | Chemical linkers and cleavable substrates and conjugates thereof | MEDAREX, INC. (US) | 2013-06-11 | — | — | US | disclosed |
| US-8461117-B2 | Chemical linkers and cleavable substrates and conjugates thereof | MEDAREX, INC. (US) | 2013-06-11 | — | — | US | disclosed |
| EP-2121667-A2 | CHEMICAL LINKERS WITH SINGLE AMINO ACIDS AND CONJUGATES THEREOF | Medarex Inc. (US) | 2009-11-25 | — | — | EP | disclosed |
| EP-2114454-A2 | CHEMICAL LINKERS AND CLEAVABLE SUBSTRATES AND CONJUGATES THEREOF | Medarex, Inc. (US) | 2009-11-11 | — | — | EP | disclosed |
| WO-2008103693-A2 | CHEMICAL LINKERS WITH SINGLE AMINO ACIDS AND CONJUGATES THEREOF | MEDAREX, INC. (US) | 2008-08-28 | — | — | WO | disclosed |
| WO-2008103693-A2 | CHEMICAL LINKERS WITH SINGLE AMINO ACIDS AND CONJUGATES THEREOF | MEDAREX, INC. (US) | 2008-08-28 | — | — | WO | disclosed |
| WO-2008083312-A2 | CHEMICAL LINKERS AND CLEAVABLE SUBSTRATES AND CONJUGATES THEREOF | MEDAREX, INC. (US) | 2008-07-10 | — | — | WO | disclosed |
| WO-2008083312-A2 | CHEMICAL LINKERS AND CLEAVABLE SUBSTRATES AND CONJUGATES THEREOF | MEDAREX, INC. (US) | 2008-07-10 | — | — | WO | disclosed |
| US-7297495-B2 | Hybridization-triggered fluorescent detection of nucleic acids | EPOCH BIOSCIENCES, INC. (US) | 2007-11-20 | — | — | US | disclosed |
| US-7297495-B2 | Hybridization-triggered fluorescent detection of nucleic acids | EPOCH BIOSCIENCES, INC. (US) | 2007-11-20 | — | — | US | disclosed |
| US-20070166723-A1 | Hybridization-triggered fluorescent detection of nucleic acids | EPOCH BIOSCIENCES INC. (US) | 2007-07-19 | — | — | US | disclosed |
| US-20070166723-A1 | Hybridization-triggered fluorescent detection of nucleic acids | EPOCH BIOSCIENCES INC. (US) | 2007-07-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070166723-A1 | Hybridization-triggered fluorescent detection of nucleic acids | DDX21, RNGTT, NOP2 | PIM1 2814/4885PIM3 2247/4885CYP1A2 4788/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.