SCHEMBL4662729

SCHEMBL4662729

CCO[Si](CCCNC(CCC[Si](OCC)(OCC)OCC)C(C)C(=O)O)(OCC)OCC

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4661463 0.95
SCHEMBL16989796 0.95
SCHEMBL4664272 0.85
SCHEMBL28658877 0.80 TSHR (0.33)
SCHEMBL29066700 0.75 BLM (0.44)
SCHEMBL4662722 0.75 ALDH1A1 (0.33)
SCHEMBL8959221 0.74 TDP1 (0.33)
SCHEMBL1367286 0.74 EPHX2 (0.34)
SCHEMBL7089238 0.74
SCHEMBL1367282 0.74 EPHX2 (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1971656-B1 SILYLATED POLYURENTHANE-POLYUREA PROTECTIVE COATING COMPOSITIONS MOMENTIVE PERFORMANCE MAT INC (US) 2013-07-24 EP claimed
EP-1877452-B1 SCRATCH RESISTANT CURABLE COATING COMPOSITION SHERWIN WILLIAMS CO (US) 2008-12-24 EP claimed
US-20210207011-A1 COMPOSITIONS CONTAINING ISOCYANATE FUNCTIONAL PREPOLYMERS AND QUATERNARY AMMONUM MODIFIED NANOCLAYS DOW GLOBAL TECHNOLOGIES LLC (US) 2021-07-08 US disclosed
EP-3416995-A1 COMPOSITIONS CONTAINING ISOCYANATE FUNCTIONAL PREPOLYMERS AND QUATERNARY AMMONIUM MODIFIED NANOCLAYS Dow Global Technologies LLC (US) 2018-12-26 EP disclosed
WO-2017142714-A1 COMPOSITIONS CONTAINING ISOCYANATE FUNCTIONAL PREPOLYMERS AND QUATERNARY AMMONIUM MODIFIED NANOCLAYS DOW GLOBAL TECHNOLOGIES LLC (US) 2017-08-24 WO disclosed
US-9499727-B2 Curable compositions containing isocyanate functional components having improved durability DOW GLOBAL TECHNOLOGIES LLC (US) 2016-11-22 US disclosed
US-20150175860-A1 CURABLE COMPOSITIONS CONTAINING ISOCYANATE FUNCTIONAL COMPONENTS HAVING IMPROVED DURABILITY DOW EUROPE GMBH (CH) 2015-06-25 US disclosed
WO-2013016133-A2 A ONE-COMPONENT, DUAL-CURE ADHESIVE FOR USE ON ELECTRONICS H.B. FULLER COMPANY (US) 2013-01-31 WO disclosed
EP-0232971-A2 Clear, weather resistant adherent coating MORTON INTERNATIONAL, INC. (US) 1987-08-19 EP disclosed
US-4640868-A CURABLE REACTION PRODUCT OF ISOCYANURATE POLYISOCYANATE AND AMINO DISILANE MORTON THIOKOL INC. (US) 1987-02-03 US disclosed