SCHEMBL4664272

SCHEMBL4664272

CO[Si](CCCNC(CCC[Si](OC)(OC)OC)C(C)C(=O)O)(OC)OC

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4661463 0.92
SCHEMBL16989796 0.92
SCHEMBL4662729 0.85
SCHEMBL19281470 0.79 TSHR (0.34)
SCHEMBL31556023 0.76 SMN1; SMN2 (0.41)
SCHEMBL28429179 0.73 BLM (0.47)
SCHEMBL27545312 0.73 MAPK1 (0.33)
SCHEMBL4661473 0.73 APAF1 (0.33)
SCHEMBL6344840 0.73 LDHA (0.33)
SCHEMBL23795579 0.72 MEN1 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1971656-B1 SILYLATED POLYURENTHANE-POLYUREA PROTECTIVE COATING COMPOSITIONS MOMENTIVE PERFORMANCE MAT INC (US) 2013-07-24 EP claimed
EP-1877452-B1 SCRATCH RESISTANT CURABLE COATING COMPOSITION SHERWIN WILLIAMS CO (US) 2008-12-24 EP claimed
EP-1877452-B1 SCRATCH RESISTANT CURABLE COATING COMPOSITION SHERWIN WILLIAMS CO (US) 2008-12-24 EP disclosed
EP-0232971-A2 Clear, weather resistant adherent coating MORTON INTERNATIONAL, INC. (US) 1987-08-19 EP disclosed
US-4640868-A CURABLE REACTION PRODUCT OF ISOCYANURATE POLYISOCYANATE AND AMINO DISILANE MORTON THIOKOL INC. (US) 1987-02-03 US disclosed