SCHEMBL4662744

SCHEMBL4662744

C=C(C)C(=O)NCCC(NC)NC

nearest known ligand 0.36

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TGFBR1 P36897 1/20 0.36
ANPEP P15144 3/20 0.33
RNPEP Q9H4A4 3/20 0.33
DNPEP Q9ULA0 2/20 0.33
SMN1; SMN2 Q16637 3/20 0.32
RAB9A P51151 2/20 0.32
GAA P10253 1/20 0.32
NPC1 O15118 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
MTNR1A P48039 1/20 0.31
MTNR1B P49286 1/20 0.31
RXFP1 Q9HBX9 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21798971 0.85 SMN1; SMN2 (0.40) ANPEPRNPEPDNPEPSMN1; SMN2RAB9A
SCHEMBL98539 0.79 TGFBR1 (0.38) TGFBR1ANPEPRNPEPDNPEPSMN1; SMN2
SCHEMBL3235398 0.79 ANPEP (0.52) TGFBR1ANPEPRNPEPDNPEPSMN1; SMN2
SCHEMBL316224 0.78 TGFBR1 (0.41) TGFBR1SMN1; SMN2RAB9ANPC1RXFP1
SCHEMBL7129431 0.78 ANPEP (0.42) TGFBR1ANPEPRNPEPDNPEPSMN1; SMN2
Ammonia Solution, Strong SCHEMBL28096709 0.78 TGFBR1 (0.37) TGFBR1ANPEPRNPEPDNPEPSMN1; SMN2
SCHEMBL14413834 0.78 TGFBR1 (0.37) TGFBR1ANPEPRNPEPDNPEPSMN1; SMN2
SCHEMBL157717 0.78 ALDH1A1 (0.45) TGFBR1ANPEPRNPEPDNPEPSMN1; SMN2
SCHEMBL5722555 0.76 ANPEP (0.44) TGFBR1ANPEPRNPEPDNPEPSMN1; SMN2
SCHEMBL7757017 0.74 TGFBR1 (0.35) TGFBR1ANPEPRNPEPDNPEPSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11458723-B2 Support material formulation and additive manufacturing processes employing same STRATASYS LTD. (IL) 2022-10-04 US claimed
US-20200369020-A1 SUPPORT MATERIAL FORMULATION AND ADDITIVE MANUFACTURING PROCESSES EMPLOYING SAME STRATASYS LTD. (IL) 2020-11-26 US claimed
US-6110454-A SOLUTIONS OF COPOLYMERS OF VINYLPYRROLIDONE AND DIMETHYLAMINO PROPYLMETHACRYLAMIDE FORMED BY CATALYTIC POLYMERIZATION ISP INVESTMENTS INC. (US) 2000-08-29 US claimed
EP-0857054-A4 PROCESS FOR MAKING SUBSTANTIALLY HOMOGENEOUS COPOLYMERS OF VINYL PYRROLIDONE AND N-3,3-DIMETHYLAMINOPROPYL METHACRYLAMIDE FOR PERSONAL CARE APPLICATIONS ISP INVESTMENTS INC (US) 1998-12-09 EP claimed
EP-0857054-A1 PROCESS FOR MAKING SUBSTANTIALLY HOMOGENEOUS COPOLYMERS OF VINYL PYRROLIDONE AND N-3,3-DIMETHYLAMINOPROPYL METHACRYLAMIDE FOR PERSONAL CARE APPLICATIONS ISP INVESTMENTS INC. (US) 1998-08-12 EP claimed
US-5609865-A FOR HAIR STYLING ISP INVESTMENTS INC. (US) 1997-03-11 US claimed
WO-1996019967-A1 PROCESS FOR MAKING SUBSTANTIALLY HOMOGENEOUS COPOLYMERS OF VINYL PYRROLIDONE AND N-3,3-DIMETHYLAMINOPROPYL METHACRYLAMIDE FOR PERSONAL CARE APPLICATIONS ISP INVESTMENTS INC. (US) 1996-07-04 WO claimed
US-11780172-B2 Water-breakable formulations and additive manufacturing processes employing same STRATASYS LTD. (IL) 2023-10-10 US disclosed
EP-3334590-B1 CLEANING COMPOSITION STRATASYS LTD (IL) 2023-06-07 EP disclosed
US-11458723-B2 Support material formulation and additive manufacturing processes employing same STRATASYS LTD. (IL) 2022-10-04 US disclosed
CN-107533296-B Support material preparation and lamination manufacturing process using the same 斯特拉塔西斯公司 2021-11-09 CN disclosed
US-11167499-B2 Cleaning composition STRATASYS LTD. (IL) 2021-11-09 US disclosed
EP-3268809-B1 SUPPORT MATERIAL FORMULATION AND ADDITIVE MANUFACTURING PROCESSES EMPLOYING SAME STRATASYS LTD (IL) 2021-10-13 EP disclosed
EP-0857054-A1 PROCESS FOR MAKING SUBSTANTIALLY HOMOGENEOUS COPOLYMERS OF VINYL PYRROLIDONE AND N-3,3-DIMETHYLAMINOPROPYL METHACRYLAMIDE FOR PERSONAL CARE APPLICATIONS ISP INVESTMENTS INC. (US) 1998-08-12 EP disclosed
CN-1170347-A Substantially homogeneous copolymers of vinyl pyrrolidone and N-3, 3 dimethylaminopropyl methacrylamide for personal care applications ISP INVESTMENTS INC (US) 1998-01-14 CN disclosed
US-5609865-A FOR HAIR STYLING ISP INVESTMENTS INC. (US) 1997-03-11 US disclosed
US-5609865-A FOR HAIR STYLING ISP INVESTMENTS INC. (US) 1997-03-11 US disclosed
US-5609865-A FOR HAIR STYLING ISP INVESTMENTS INC. (US) 1997-03-11 US disclosed
WO-1996019967-A1 PROCESS FOR MAKING SUBSTANTIALLY HOMOGENEOUS COPOLYMERS OF VINYL PYRROLIDONE AND N-3,3-DIMETHYLAMINOPROPYL METHACRYLAMIDE FOR PERSONAL CARE APPLICATIONS ISP INVESTMENTS INC. (US) 1996-07-04 WO disclosed
WO-1996019967-A1 PROCESS FOR MAKING SUBSTANTIALLY HOMOGENEOUS COPOLYMERS OF VINYL PYRROLIDONE AND N-3,3-DIMETHYLAMINOPROPYL METHACRYLAMIDE FOR PERSONAL CARE APPLICATIONS ISP INVESTMENTS INC. (US) 1996-07-04 WO disclosed