Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | USP1 | O94782 | 1/20 | 0.36 |
| ▸ | WDR48 | Q8TAF3 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14116707 | 1.00 | NAAA (0.38) | NAAAHSD17B10ALDH1A1MMP9LMNA | |
| SCHEMBL30559598 | 1.00 | NAAA (0.38) | NAAAHSD17B10ALDH1A1MMP9LMNA | |
| SCHEMBL19365539 | 0.82 | ALDH1A1 (0.40) | HSD17B10ALDH1A1MMP9MAOBUSP1 | |
| SCHEMBL231311 | 0.82 | CYP2D6 (0.41) | NAAAHSD17B10ALDH1A1MMP9MAOB | |
| SCHEMBL6751629 | 0.82 | CYP2D6 (0.41) | NAAAHSD17B10ALDH1A1MMP9MAOB | |
| SCHEMBL6428933 | 0.82 | ALDH1A1 (0.40) | HSD17B10ALDH1A1MMP9MAOBUSP1 | |
| SCHEMBL159785 | 0.82 | CYP2D6 (0.41) | NAAAHSD17B10ALDH1A1MMP9MAOB | |
| SCHEMBL14116703 | 0.82 | CYP2D6 (0.41) | NAAAHSD17B10ALDH1A1MMP9MAOB | |
| SCHEMBL6428936 | 0.82 | ALDH1A1 (0.40) | HSD17B10ALDH1A1MMP9MAOBUSP1 | |
| SCHEMBL8030536 | 0.74 | NPC1 (0.37) | ALDH1A1MMP9MAOBUSP1WDR48 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080064736-A1 | Substituted 2-Pyrrolidone Derivatives as Fungicides and Insecticides | BAYER CROPSCIENCE AG (DE) | 2008-03-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080064736-A1 | Substituted 2-Pyrrolidone Derivatives as Fungicides and Insecticides | DDT, PPM1F, PPM1D | NAAA 3372/4885HSD17B10 902/4885ALDH1A1 1151/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.