Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | USP1 | O94782 | 1/20 | 0.34 |
| ▸ | WDR48 | Q8TAF3 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8030538 | 1.00 | NPC1 (0.37) | NPC1RAB9ASMN1; SMN2MMP9ALDH1A1 | |
| SCHEMBL8021211 | 0.86 | MMP9 (0.43) | NPC1RAB9ASMN1; SMN2MMP9ALDH1A1 | |
| SCHEMBL8021209 | 0.86 | MMP9 (0.43) | NPC1RAB9ASMN1; SMN2MMP9ALDH1A1 | |
| SCHEMBL8037028 | 0.83 | BACE1 (0.43) | SMN1; SMN2MMP9ALDH1A1MAPTITGA4 | |
| SCHEMBL8037033 | 0.83 | BACE1 (0.43) | SMN1; SMN2MMP9ALDH1A1MAPTITGA4 | |
| SCHEMBL8032384 | 0.81 | CACNA1G (0.37) | NPC1RAB9ASMN1; SMN2MMP9ALDH1A1 | |
| SCHEMBL6428936 | 0.79 | ALDH1A1 (0.40) | MMP9ALDH1A1MAPTITGA4POLB | |
| SCHEMBL19365539 | 0.79 | ALDH1A1 (0.40) | MMP9ALDH1A1MAPTITGA4POLB | |
| SCHEMBL6428933 | 0.79 | ALDH1A1 (0.40) | MMP9ALDH1A1MAPTITGA4POLB | |
| SCHEMBL8021205 | 0.77 | MMP9 (0.39) | NPC1RAB9ASMN1; SMN2MMP9MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6127546-A | Process for the preparation of oxazoline compound | DONG KOOK PHARMACEUTICAL CO., LTD. (KR) | 2000-10-03 | — | — | US | disclosed |