SCHEMBL466328

SCHEMBL466328

O=C(O)C(C(=O)O)(C1CO1)C1C(C(C(=O)O)(C(=O)O)C2CO2)[C@H]2C=C[C@@H]1C2

nearest known ligand 0.31

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.31
POLB P06746 1/20 0.30
APEX1 P27695 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL933740 1.00 LMNA (0.31) LMNAPOLBAPEX1TDP1
SCHEMBL28397344 0.71 KDM4E (0.31) LMNA
SCHEMBL4850872 0.69 TP53 (0.33)
SCHEMBL5050657 0.69
SCHEMBL13843176 0.63 POLB (0.34) LMNAPOLBAPEX1TDP1
SCHEMBL22361976 0.60 POLB (0.46) POLBAPEX1TDP1
SCHEMBL3294119 0.60 POLB (0.46) POLBAPEX1TDP1
SCHEMBL18021020 0.59 POLB (0.45) POLBAPEX1TDP1
SCHEMBL17803830 0.59 POLB (0.35) POLBAPEX1TDP1
SCHEMBL202551 0.59 ALDH1A1 (0.32) TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2467432-A1 SUPRAMOLECULAR POLYMER-CONTAINING BITUMINOUS COMPOSITION CECA S.A. (FR) 2012-06-27 EP claimed
WO-2011020847-A1 SUPRAMOLECULAR POLYMER-CONTAINING BITUMINOUS COMPOSITION CECA S.A. (FR) 2011-02-24 WO claimed
WO-2009120211-A1 POLYMERIC COMPOSITIONS FOR PLASTIC STRAPPING BASF CORPORATION (US) 2009-10-01 WO claimed
US-11688529-B2 Semi-conductive polymer composition BOREALIS AG (AT) 2023-06-27 US disclosed
EP-2956300-B1 USE OF SEMI-AROMATIC COPOLYAMIDE FOR TRANSPORTING REFRIGERANT FLUID ARKEMA FRANCE (FR) 2023-04-12 EP disclosed
EP-2956301-B1 THERMOPLASTIC STRUCTURE FOR TRANSPORTING REFRIGERANT FLUID ARKEMA FRANCE (FR) 2021-03-24 EP disclosed
US-10513150-B2 Diene rubber/polypropylene thermoplastic elastomer copolymer, compositions containing same, and preparation method COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2019-12-24 US disclosed
US-20180170106-A1 DIENE RUBBER/POLYPROPYLENE THERMOPLASTIC ELASTOMER COPOLYMER, COMPOSITIONS CONTAINING SAME, AND PREPARATION METHOD COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2018-06-21 US disclosed
US-9668475-B2 Photocatalytic film for soil fumigation ARKEMA FRANCE (FR) 2017-06-06 US disclosed
EP-2956301-A1 THERMOPLASTIC STRUCTURE FOR TRANSPORTING REFRIGERANT FLUID Arkema France (FR) 2015-12-23 EP disclosed
EP-2956300-A1 USE OF SEMI-AROMATIC COPOLYAMIDE FOR TRANSPORTING REFRIGERANT FLUID Arkema France (FR) 2015-12-23 EP disclosed
WO-2001010951-A1 ANTISTATIC STYRENE POLYMER COMPOSITIONS ATOFINA (FR) 2001-02-15 WO disclosed
EP-0963412-A1 SHOCKPROOF POLYESTER-INJECTED PARTS Elf Atochem S.A. (FR) 1999-12-15 EP disclosed
WO-1999033917-A1 SHOCKPROOF POLYESTER-INJECTED PARTS ELF ATOCHEM S.A. (FR) 1999-07-08 WO disclosed
EP-0802227-A1 Injection moulded polyamide articles comprising an impact modifier with a particular distribution in the polyamide ELF ATOCHEM S.A. (FR) 1997-10-22 EP disclosed
EP-0802226-A1 Impact-resistant injection-moulded polyamide articles ELF ATOCHEM S.A. (FR) 1997-10-22 EP disclosed
US-5254626-A Blend; aromatic polyester; elastomeric copolymer of ethylene, an alkyl (meth)acrylate and an unsaturated epoxide; another elastomer containing amido-aminic and/or imido-aminic functionalized units ISTITUTO GUIDO DONEGANI S.P.A. (IT) 1993-10-19 US disclosed
EP-0535744-A2 Polyester based high-tenacity, high-impact thermoplastic compositions ENICHEM S.p.A. (IT) 1993-04-07 EP disclosed
EP-0529703-A1 High-tenacity, high-impact-strength thermoplastic polyester compositions ENICHEM S.p.A. (IT) 1993-03-03 EP disclosed
EP-0484273-A1 Poly(aryene sulphide) compositions CIBA-GEIGY AG (CH) 1992-05-06 EP disclosed