Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | NR0B1 | P51843 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 10/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.37 |
| ▸ | UBE2N | P61088 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4663204 | 0.84 | NR0B1 (0.44) | NR0B1POLBLMNASMN1; SMN2 | |
| SCHEMBL4241441 | 0.81 | NR0B1 (0.48) | NR0B1POLBLMNASMN1; SMN2 | |
| SCHEMBL4664820 | 0.81 | NR0B1 (0.42) | NR0B1POLBLMNASMN1; SMN2 | |
| SCHEMBL4664683 | 0.77 | NR0B1 (0.45) | NR0B1POLBLMNASMN1; SMN2 | |
| SCHEMBL4664915 | 0.75 | NPC1 (0.48) | NR0B1POLBLMNASMN1; SMN2 | |
| SCHEMBL4244260 | 0.75 | KMT2A (0.54) | NR0B1POLBLMNASMN1; SMN2 | |
| SCHEMBL4664885 | 0.75 | NR0B1 (0.43) | NR0B1POLBLMNASMN1; SMN2 | |
| SCHEMBL4664783 | 0.75 | CTSS (0.48) | — | |
| SCHEMBL4663019 | 0.72 | NR0B1 (0.44) | NR0B1POLBLMNASMN1; SMN2 | |
| SCHEMBL4664860 | 0.72 | PTGS2 (0.46) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080132562-A1 | TETRONIC AND TETRAMIC ACIDS | GODEL THIERRY | 2008-06-05 | — | — | US | claimed |
| US-20050119329-A1 | Tetronic and tetramic acids | HOFFMANN-LA ROCHE INC. | 2005-06-02 | — | — | US | claimed |
| US-20080132562-A1 | TETRONIC AND TETRAMIC ACIDS | GODEL THIERRY | 2008-06-05 | — | — | US | disclosed |
| US-20050119329-A1 | Tetronic and tetramic acids | HOFFMANN-LA ROCHE INC. | 2005-06-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080132562-A1 | TETRONIC AND TETRAMIC ACIDS | BACE1, PSEN1, BACE2 | EPHX1 2108/4885NR0B1 106/4885CHRM1 36/4885 |
| US-20050119329-A1 | Tetronic and tetramic acids | BACE1, PSEN1, BACE2 | EPHX1 2108/4885NR0B1 106/4885CHRM1 36/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.