Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 14/20 | 0.52 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.42 |
| ▸ | FEN1 | P39748 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17148650 | 0.90 | GPR119 (0.47) | GPR119FAAHKDM4EPKMALOX5AP | |
| SCHEMBL17140183 | 0.83 | ALOX5AP (0.48) | GPR119FAAHKDM4EPKMALOX5AP | |
| SCHEMBL4663367 | 0.82 | GPR119 (0.41) | GPR119PIK3CD | |
| SCHEMBL4666833 | 0.82 | GPR119 (0.53) | GPR119FAAHKDM4EPKMALOX5AP | |
| SCHEMBL4665126 | 0.80 | GPR119 (0.52) | GPR119FAAHKDM4EPKMALOX5AP | |
| SCHEMBL17837497 | 0.79 | AXL (0.51) | GPR119FAAHALOX5APFEN1 | |
| SCHEMBL18228326 | 0.78 | KDM4E (0.47) | GPR119FAAHKDM4EPKMALOX5AP | |
| SCHEMBL28486392 | 0.76 | GPR119 (0.47) | GPR119KDM4EALOX5APFEN1 | |
| SCHEMBL29482678 | 0.76 | GPR119 (0.47) | GPR119KDM4EALOX5APFEN1 | |
| SCHEMBL29186940 | 0.76 | GPR119 (0.48) | GPR119FAAHKDM4EPKMALOX5AP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080242685-A1 | Chemical Compounds | SMITHKLINE BEECHAM CORPORATION | 2008-10-02 | — | — | US | disclosed |
| US-20080242685-A1 | Chemical Compounds | SMITHKLINE BEECHAM CORPORATION | 2008-10-02 | — | — | US | disclosed |
| US-20080242685-A1 | Chemical Compounds | SMITHKLINE BEECHAM CORPORATION | 2008-10-02 | — | — | US | disclosed |
| EP-1940296-A2 | CHEMICAL COMPOUNDS | SmithKline Beecham Corporation (US) | 2008-07-09 | — | — | EP | disclosed |
| WO-2007114848-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-10-11 | — | — | WO | disclosed |
| WO-2007114848-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-10-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080242685-A1 | Chemical Compounds | NFKBIA, IKBKG, NFKB2 | GPR119 2751/4885PIK3CD 144/4885FAAH 2586/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.