Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 10/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31309362 | 0.83 | KDM4E (0.41) | KDM4EALDH1A1MAPTGLAATM | |
| SCHEMBL31309635 | 0.83 | ALDH1A1 (0.42) | KDM4EALDH1A1MAPTHSD17B10GAA | |
| SCHEMBL6885011 | 0.80 | ADORA2A (0.47) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL6883434 | 0.80 | ADORA2A (0.46) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL4662514 | 0.80 | MAPT (0.46) | KDM4EALDH1A1MAPTHPGDGAA | |
| SCHEMBL6884470 | 0.79 | ADORA2A (0.69) | KDM4EALDH1A1HPGDGLAADORA2A | |
| SCHEMBL6871457 | 0.77 | ADORA2A (0.66) | GAAADORA2A | |
| SCHEMBL6879422 | 0.76 | ALDH1A1 (0.43) | ALDH1A1HPGDADORA2ANPSR1 | |
| SCHEMBL6886208 | 0.76 | ADORA2A (0.67) | ADORA2A | |
| SCHEMBL6882930 | 0.76 | ADORA2A (0.67) | KDM4EALDH1A1MAPTHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080033006-A1 | 1,2,4-Triazolo[ 1,5-A] Pyridines as Gastric Acid Secretion Inhibitors | ALTANA PHARMA AG (DE) | 2008-02-07 | — | — | US | disclosed |
| EP-1711498-A2 | 1,2,4-TRIAZOLO¬1,5-A|PYRIDINES AS GASTRIC ACID SECRETION INHIBITORS | Altana Pharma AG (DE) | 2006-10-18 | — | — | EP | disclosed |
| WO-2005070927-A2 | 1,2,4-TRIAZOLO[1,5-A] PYRIDINES AS GASTRIC ACID SECRETION INHIBITORS | ALTANA PHARMA AG (DE) | 2005-08-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080033006-A1 | 1,2,4-Triazolo[ 1,5-A] Pyridines as Gastric Acid Secretion Inhibitors | CCKBR, GIPR, PGA5 | KDM4E 2527/4885ALDH1A1 715/4885MAPT 4732/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.