Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TRPV3 | Q8NET8 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 3/20 | 0.42 |
| ▸ | TPH1 | P17752 | 1/20 | 0.41 |
| ▸ | ACP1 | P24666 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.40 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.40 |
| ▸ | MGAM | O43451 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.39 |
| ▸ | TACR3 | P29371 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14315379 | 0.81 | SMN1; SMN2 (0.50) | KDM1AMAOAMAOBMEN1KMT2A | |
| SCHEMBL8624930 | 0.79 | ADRB2 (0.44) | TRPV3CYP1A2ADRB2SMN1; SMN2 | |
| SCHEMBL12890740 | 0.77 | KDM1A (0.50) | KDM1AMAOAMAOBKMT2ATRPV3 | |
| SCHEMBL4350261 | 0.76 | LMNA (0.52) | KDM1AMAOAMAOBMEN1KMT2A | |
| SCHEMBL4357737 | 0.76 | LMNA (0.52) | KDM1AMAOAMAOBMEN1KMT2A | |
| SCHEMBL4662644 | 0.76 | LMNA (0.52) | KDM1AMAOAMAOBMEN1KMT2A | |
| SCHEMBL424037 | 0.76 | SMN1; SMN2 (0.61) | MEN1KMT2AADRB2ALDH1A1HPGD | |
| SCHEMBL4853220 | 0.76 | SMN1; SMN2 (0.61) | MEN1KMT2AADRB2ALDH1A1HPGD | |
| SCHEMBL1848481 | 0.76 | SMN1; SMN2 (0.61) | MEN1KMT2AADRB2ALDH1A1HPGD | |
| SCHEMBL7205515 | 0.74 | KDM1A (0.48) | KDM1AMAOAMAOBKMT2ATRPV3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2007707-A1 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | Boehringer Ingelheim International GmbH (DE) | 2008-12-31 | — | — | EP | disclosed |
| WO-2007118041-A1 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-10-18 | — | — | WO | disclosed |