Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XPO1 | O14980 | 1/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 15/20 | 0.38 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3285028 | 0.79 | DRD4 (0.46) | XPO1TBXA2RCHRM1ADRA2BADRA2C | |
| SCHEMBL13324277 | 0.78 | TBXA2R (0.43) | XPO1TBXA2RDRD2DRD4MAOB | |
| SCHEMBL13324268 | 0.77 | KCNA3 (0.49) | XPO1DRD2DRD4DRD3 | |
| Hydrochloric Acid SCHEMBL3281041 | 0.77 | TBXA2R (0.42) | XPO1TBXA2RDRD2DRD4MAOB | |
| SCHEMBL13324269 | 0.75 | TBXA2R (0.41) | XPO1TBXA2RDRD4MAOBADRA1A | |
| SCHEMBL15758902 | 0.72 | KCNJ1 (0.64) | KCNH2 | |
| SCHEMBL707084 | 0.71 | DRD2 (0.42) | OPRM1DRD2DRD3KCNH2 | |
| SCHEMBL5171694 | 0.69 | OPRM1 (0.57) | OPRM1SLC22A1NR1I2ABCB1CHRM1 | |
| SCHEMBL3100183 | 0.69 | OPRM1 (0.37) | OPRM1SLC22A1NR1I2ABCB1CHRM1 | |
| SCHEMBL4125301 | 0.68 | ACHE (0.57) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2007377-A2 | ANTIBACTERIAL AGENTS | Glaxo Group Limited (GB) | 2008-12-31 | — | — | EP | disclosed |
| WO-2007118130-A2 | ANTIBACTERIAL AGENTS | GLAXO GROUP LIMITED (GB) | 2007-10-18 | — | — | WO | disclosed |