Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
| ▸ | HPGDS | O60760 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | FNTA | P49354 | 1/20 | 0.33 |
| ▸ | FNTB | P49356 | 1/20 | 0.33 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30832037 | 0.87 | MBOAT4 (0.43) | ALDH1A1KDM4EHPGDL3MBTL1HTT | |
| SCHEMBL1145890 | 0.80 | KDM4E (0.42) | ALDH1A1KDM4EHPGDL3MBTL1HTT | |
| SCHEMBL7219997 | 0.78 | CYP19A1 (0.45) | ALDH1A1KDM4EHPGDL3MBTL1HTT | |
| SCHEMBL2633134 | 0.77 | CYP2A6 (0.48) | ALDH1A1KDM4EHPGDL3MBTL1HTT | |
| SCHEMBL10263917 | 0.76 | SYK (0.40) | ALDH1A1KDM4EHPGDL3MBTL1GABRA5 | |
| SCHEMBL13141087 | 0.76 | MBOAT4 (0.42) | ALDH1A1KDM4EHPGDL3MBTL1HTT | |
| SCHEMBL1145885 | 0.76 | MBOAT4 (0.39) | ALDH1A1KDM4EHPGDL3MBTL1HTT | |
| SCHEMBL2578930 | 0.75 | MBOAT4 (0.40) | ALDH1A1KDM4EHPGDL3MBTL1HTT | |
| SCHEMBL19387952 | 0.75 | RORC (0.40) | ALDH1A1KDM4EHPGDL3MBTL1HTT | |
| SCHEMBL7433167 | 0.75 | ALDH1A1 (0.49) | ALDH1A1KDM4EHPGDL3MBTL1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1924561-A2 | 6-ARYLALKYLAMINO- 2,3,4,5-TETRAHYDRO-1H-BENZO[D]AZEPINES AS 5-HT2C RECEPTOR AGONISTS | Eli Lilly & Company (US) | 2008-05-28 | — | — | EP | disclosed |
| WO-2007028083-A2 | 6-ARYLALKYLAMINO- 2,3,4,5-TETRAHYDRO-1H-BENZO[D]AZEPINES AS 5-HT2C RECEPTOR AGONISTS | ELI LILLY AND COMPANY (US) | 2007-03-08 | — | — | WO | disclosed |