Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.32 |
| ▸ | ITK | Q08881 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4664854 | 0.85 | KMT2A (0.34) | ALDH1A1HSD11B1KMT2AGAA | |
| SCHEMBL4663226 | 0.84 | KMT2A (0.33) | HSD11B1KMT2AITK | |
| SCHEMBL4666499 | 0.83 | CYP2C9 (0.37) | HSD11B1KMT2AKEAP1NFE2L2 | |
| SCHEMBL4963473 | 0.77 | SMN1; SMN2 (0.41) | ALDH1A1KMT2ALMNA | |
| SCHEMBL4964535 | 0.77 | PDK1 (0.35) | ALDH1A1HSD11B1LMNAGAAPKM | |
| SCHEMBL4963781 | 0.76 | CTNNB1 (0.35) | ALDH1A1HSD17B10KMT2AGAABRD4 | |
| SCHEMBL4739384 | 0.74 | PARP1 (0.35) | ALDH1A1HSD17B10PARP1PKMBRD4 | |
| SCHEMBL4964235 | 0.74 | CTNNB1 (0.37) | — | |
| SCHEMBL5666743 | 0.73 | ALDH1A1 (0.34) | ALDH1A1HSD17B10ALOX15PARP1HTR2B | |
| SCHEMBL4964361 | 0.73 | IDO1 (0.38) | PKMBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080113963-A1 | Cyclic benzimidazoles | ALTANA PHARMA AG (DE) | 2008-05-15 | — | — | US | disclosed |
| US-7307084-B2 | Cyclic benzimidazoles | ALTANA PHARMA AG (DE) | 2007-12-11 | — | — | US | disclosed |
| US-20060194968-A1 | Cyclic benizimidazoles | ALTANA PHARMA AG (DE) | 2006-08-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060194968-A1 | Cyclic benizimidazoles | VIP, SI, GIPR | ALDH1A1 293/4885HSD17B10 2233/4885ALOX15 1681/4885 |
| US-20080113963-A1 | Cyclic benzimidazoles | VIP, GIPR, SI | ALDH1A1 2588/4885HSD17B10 2661/4885ALOX15 2145/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.