Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 5/20 | 0.71 |
| ▸ | NR3C1 | P04150 | 13/20 | 0.67 |
| ▸ | PGR | P06401 | 12/20 | 0.67 |
| ▸ | ESR1 | P03372 | 3/20 | 0.59 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.59 |
| ▸ | THRA | P10827 | 1/20 | 0.59 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | THPO | P40225 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5395107 | 1.00 | AR (0.71) | ARNR3C1PGRESR1ESR2 | |
| SCHEMBL9647584 | 0.93 | AR (0.62) | ARNR3C1PGRESR1ESR2 | |
| SCHEMBL10399827 | 0.92 | AR (0.67) | ARNR3C1PGRESR1ESR2 | |
| SCHEMBL15094157 | 0.92 | AR (0.67) | ARNR3C1PGRESR1ESR2 | |
| SCHEMBL4664713 | 0.92 | AR (0.67) | ARNR3C1PGRESR1ESR2 | |
| SCHEMBL3678661 | 0.92 | AR (0.67) | ARNR3C1PGRESR1ESR2 | |
| SCHEMBL14670184 | 0.92 | AR (0.60) | ARNR3C1PGRESR1ESR2 | |
| SCHEMBL14666174 | 0.91 | AR (0.73) | ARNR3C1PGRESR1ESR2 | |
| SCHEMBL14656729 | 0.91 | AR (0.73) | ARNR3C1PGRESR1ESR2 | |
| SCHEMBL1488533 | 0.88 | AR (0.77) | ARNR3C1PGRESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7256185-B1 | Control of selective estrogen receptor modulators | EASTERN VIRGINIA MEDICAL SCHOOL (US) | 2007-08-14 | — | — | US | disclosed |
| US-6653297-B1 | Synergistic treatment with progestationally active material; reducing side effects | MEDICAL COLLEGE OF HAMPTON ROADS | 2003-11-25 | — | — | US | disclosed |
| US-20030181431-A1 | CONTROL OF SELECTIVE ESTROGEN RECEPTOR MODULATORS | EASTERN VIRGINIA MEDICAL SCHOOL | 2003-09-25 | — | — | US | disclosed |
| EP-0888775-A2 | Control of selective estrogen receptor modulators | MEDICAL COLLEGE OF HAMPTON ROADS (US) | 1999-01-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030181431-A1 | CONTROL OF SELECTIVE ESTROGEN RECEPTOR MODULATORS | SHBG, ESR2, ESR1 | AR 10/4885NR3C1 45/4885PGR 14/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.