Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.56 |
| ▸ | PPARD | Q03181 | 1/20 | 0.56 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.56 |
| ▸ | PPARG | P37231 | 2/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CPA1 | P15085 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | UBE2N | P61088 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9896517 | 0.93 | PTGS1 (0.57) | PPARAPPARDEPHX1PPARGPTGS1 | |
| SCHEMBL3079795 | 0.87 | EPHX1 (0.71) | EPHX1PTGS1CYP2C19P4HTMCPA1 | |
| SCHEMBL599399 | 0.87 | EPHX1 (0.71) | EPHX1PTGS1CYP2C19P4HTMCPA1 | |
| SCHEMBL67234 | 0.87 | EPHX1 (0.71) | EPHX1PTGS1CYP2C19P4HTMCPA1 | |
| SCHEMBL6958211 | 0.86 | ESR1 (0.60) | PPARAPPARDEPHX1PPARGPTGS1 | |
| SCHEMBL28835702 | 0.86 | EPHX1 (0.77) | PPARAPPARDEPHX1PPARGCYP2C19 | |
| SCHEMBL8672896 | 0.86 | EPHX1 (0.53) | PPARAPPARDEPHX1PPARGCYP2C19 | |
| Hydrochloric Acid SCHEMBL933353 | 0.85 | EPHX1 (0.69) | EPHX1PTGS1CYP2C19P4HTMCPA1 | |
| SCHEMBL12494672 | 0.84 | CPA3 (0.50) | PPARAPPARDEPHX1PPARGPTGS1 | |
| SCHEMBL5161421 | 0.84 | ESR1 (0.61) | EPHX1PPARGPTGS1PTGS2EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3704117-B1 | AZABICYCLO DERIVATIVES FOR TREATING OCULAR DISORDERS | ALCON INC (CH) | 2026-01-28 | — | — | EP | disclosed |
| US-12247028-B2 | Azabicyclo and diazepine derivatives | ALCON INC. (CH) | 2025-03-11 | — | — | US | disclosed |
| US-20240132497-A1 | AZABICYCLO AND DIAZEPINE DERIVATIVES | ALCON INC. (CH) | 2024-04-25 | — | — | US | disclosed |
| US-11884666-B2 | Azabicyclo and diazepine derivatives | ALCON INC. (CH) | 2024-01-30 | — | — | US | disclosed |
| US-20220267328-A1 | AZABICYCLO AND DIAZEPINE DERIVATIVES | ALCON INC. (CH) | 2022-08-25 | — | — | US | disclosed |
| US-11306090-B2 | Azabicyclo and diazepine derivatives | ALCON INC. (CH) | 2022-04-19 | — | — | US | disclosed |
| US-20210179616-A1 | AZABICYCLO AND DIAZEPINE DERIVATIVES | ALCON INC. (CH) | 2021-06-17 | — | — | US | disclosed |
| US-20210179616-A1 | AZABICYCLO AND DIAZEPINE DERIVATIVES | ALCON INC. (CH) | 2021-06-17 | — | — | US | disclosed |
| CN-111247147-A | Azabicyclo and diazepatriene derivatives useful for treating ocular disorders | 爱尔康公司 | 2020-06-05 | — | — | CN | disclosed |
| CN-100591652-C | Method for producing 2-(4-fluoro-benzyl)-phenyl-acetic acid | JANSSEN PHARMACEUTICA NV | 2010-02-24 | — | — | CN | disclosed |
| CN-100591652-C | Method for producing 2-(4-fluoro-benzyl)-phenyl-acetic acid | JANSSEN PHARMACEUTICA NV | 2010-02-24 | — | — | CN | disclosed |
| US-20080132562-A1 | TETRONIC AND TETRAMIC ACIDS | GODEL THIERRY | 2008-06-05 | — | — | US | disclosed |
| CN-101006039-A | Method for producing 2-(4-fluoro-benzyl)-phenyl-acetic acid | JANSSEN PHARMACEUTICA NV (BE) | 2007-07-25 | — | — | CN | disclosed |
| CN-1886391-A | Teramic acid and threonine as beta-secretase inhibitors | HOFFMANN LA ROCHE (CH) | 2006-12-27 | — | — | CN | disclosed |
| US-20050119329-A1 | Tetronic and tetramic acids | HOFFMANN-LA ROCHE INC. | 2005-06-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11884666-B2 | Azabicyclo and diazepine derivatives | CHRM3, CHRM5, CHRNA5 | PPARA 633/4885PPARD 384/4885EPHX1 1173/4885 |
| US-20240132497-A1 | AZABICYCLO AND DIAZEPINE DERIVATIVES | CHRM3, CHRM5, CHRNA5 | PPARA 633/4885PPARD 384/4885EPHX1 1173/4885 |
| US-20210179616-A1 | AZABICYCLO AND DIAZEPINE DERIVATIVES | CHRM3, CHRM5, CHRNA5 | PPARA 633/4885PPARD 384/4885EPHX1 1173/4885 |
| US-20080132562-A1 | TETRONIC AND TETRAMIC ACIDS | BACE1, PSEN1, BACE2 | PPARA 2704/4885PPARD 2836/4885EPHX1 2108/4885 |
| US-20050119329-A1 | Tetronic and tetramic acids | BACE1, PSEN1, BACE2 | PPARA 2704/4885PPARD 2836/4885EPHX1 2108/4885 |
| US-20220267328-A1 | AZABICYCLO AND DIAZEPINE DERIVATIVES | CHRM3, CHRM5, CHRNA5 | PPARA 633/4885PPARD 384/4885EPHX1 1173/4885 |
| US-12247028-B2 | Azabicyclo and diazepine derivatives | CHRM3, CHRM5, CHRNA5 | PPARA 633/4885PPARD 384/4885EPHX1 1173/4885 |
| US-11306090-B2 | Azabicyclo and diazepine derivatives | CHRM3, CHRM5, CHRNA5 | PPARA 633/4885PPARD 384/4885EPHX1 1173/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.