Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 4/20 | 0.57 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.57 |
| ▸ | CPA1 | P15085 | 1/20 | 0.50 |
| ▸ | PPARA | Q07869 | 3/20 | 0.49 |
| ▸ | PPARD | Q03181 | 1/20 | 0.49 |
| ▸ | ESR1 | P03372 | 4/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.48 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.46 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.46 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.46 |
| ▸ | ALB | P02768 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | RARB | P10826 | 1/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4664796 | 0.93 | PPARA (0.56) | PTGS1PTGS2CPA1PPARAPPARD | |
| SCHEMBL27525650 | 0.88 | CHRM1 (0.47) | PTGS1PTGS2CPA1PPARAPPARD | |
| SCHEMBL29174149 | 0.87 | LDHA (0.59) | PTGS1PTGS2PPARAPPARDPPARG | |
| SCHEMBL6005258 | 0.87 | PTPN1 (0.49) | PTGS1PTGS2CPA1PPARAPPARD | |
| SCHEMBL9896010 | 0.86 | EPHX2 (0.51) | PTGS1PTGS2ESR2CYP2C9AKR1C3 | |
| SCHEMBL6005803 | 0.84 | PPARA (0.50) | PTGS1PTGS2PPARAPPARDESR1 | |
| SCHEMBL8873187 | 0.83 | SLC1A1 (0.56) | PTGS1PTGS2PPARAPPARDP4HTM | |
| SCHEMBL27991442 | 0.83 | EPHX1 (0.58) | PPARAP4HTMPPARGEPHX1ALDH1A1 | |
| SCHEMBL9895819 | 0.83 | KMT2A (0.52) | PTGS1PTGS2PPARAESR1ESR2 | |
| SCHEMBL30371988 | 0.82 | PTGS1 (0.44) | PTGS1PTGS2AKR1C3AKR1C2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120149718-A1 | Amido Compounds | BROTHERTON-PLEISS CHRISTINE E (US) | 2012-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149718-A1 | Amido Compounds | P2RX7, P2RX3, P2RX2 | PTGS1 1171/4885PTGS2 1485/4885CPA1 2496/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.