Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 4/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | DRD3 | P35462 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2090742 | 0.83 | CYP2A6 (0.38) | CYP2A6CYP1A2DRD3TDP1LMNA | |
| SCHEMBL6002962 | 0.83 | CYP1A2 (0.38) | CYP2A6CYP1A2DRD3TDP1LMNA | |
| SCHEMBL3985620 | 0.83 | CYP2A6 (0.38) | CYP2A6CYP1A2DRD3TDP1LMNA | |
| SCHEMBL8587770 | 0.80 | TAAR1 (0.50) | CYP2A6CYP1A2DRD3TDP1LMNA | |
| SCHEMBL10692392 | 0.79 | CYP2A6 (0.38) | CYP2A6CYP1A2ALDH1A1HTR2A | |
| SCHEMBL2091808 | 0.75 | CYP1A2 (0.34) | CYP2A6CYP1A2DRD3TDP1LMNA | |
| SCHEMBL25012755 | 0.72 | CYP1A2 (0.42) | CYP2A6CYP1A2DRD3TDP1LMNA | |
| SCHEMBL787846 | 0.72 | CYP2A6 (0.42) | CYP2A6CYP1A2ALDH1A1MIFNR4A2 | |
| SCHEMBL2092545 | 0.72 | CYP1A2 (0.42) | CYP2A6CYP1A2DRD3TDP1LMNA | |
| SCHEMBL29908309 | 0.72 | CYP2A6 (0.42) | CYP2A6CYP1A2ALDH1A1MIFNR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7323433-B2 | R-(-)-1-[2-(7-chlorobenzo[b]thiopen-3-yl-methoxy)-2-(2,4-dichlorophenyl)-ethyl]-1H-imidazole | FERRER INTERNACIONAL, S.A. (ES) | 2008-01-29 | — | — | US | disclosed |
| EP-1474422-B1 | R-(-)-1-¬2-(7-CHLOROBENZO-¬B -THIOPHEN-3-Yl-METHOXY)-2-(2,4-DICHLOROPHENYL)ETHYL -1H-IMIDAZOLE | FERRER INT (ES) | 2008-01-02 | — | — | EP | disclosed |
| US-20050065201-A1 | R-(-)-1-[2-(7- chlorobenzo[b]thiophen-3-yl- methoxy)-2-(2,4-dichlorophenyl)- ethyl]-1H-imidazole | FERRER INTERNACIONAL S.A. (ES) | 2005-03-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050065201-A1 | R-(-)-1-[2-(7- chlorobenzo[b]thiophen-3-yl- methoxy)-2-(2,4-dichlorophenyl)- ethyl]-1H-imidazole | IRF3, IRF2BP2, ARG2 | CYP2A6 2609/4885CYP1A2 696/4885DRD3 2558/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.