SCHEMBL4664967

SCHEMBL4664967

C=CCN(CC=C)c1cccs1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 3/20 0.35
SLC6A4 P31645 3/20 0.35
CYP2D6 P10635 1/20 0.35
TRPM8 Q7Z2W7 1/20 0.33
ALDH1A1 P00352 2/20 0.31
KMT2A Q03164 2/20 0.31
PKM P14618 1/20 0.31
CHKA P35790 1/20 0.31
GRIN2D O15399 1/20 0.31
GRIN3B O60391 1/20 0.31
GRIN1 Q05586 1/20 0.31
GRIN2A Q12879 1/20 0.31
GRIN2B Q13224 1/20 0.31
GRIN2C Q14957 1/20 0.31
GRIN3A Q8TCU5 1/20 0.31
CRHR1 P34998 1/20 0.31
KDM4E B2RXH2 2/20 0.30
MEN1 O00255 1/20 0.30
MAPT P10636 1/20 0.30
HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8760992 0.82 SLC6A2 (0.39) SLC6A2SLC6A4CYP2D6TRPM8ALDH1A1
SCHEMBL7034994 0.77 SLC6A2 (0.35) SLC6A2SLC6A4CYP2D6TRPM8ALDH1A1
SCHEMBL7034990 0.76 SLC6A2 (0.34) SLC6A2SLC6A4CYP2D6TRPM8ALDH1A1
SCHEMBL84280 0.71 ALDH1A1 (0.41) ALDH1A1KMT2AKDM4EMEN1MAPT
SCHEMBL7688548 0.71 TRPM8 (0.30) TRPM8
SCHEMBL15881952 0.70 KDM4E (0.34) SLC6A2SLC6A4CYP2D6ALDH1A1KMT2A
Fluoride SCHEMBL28515671 0.70 ALDH1A1 (0.40) ALDH1A1KMT2AKDM4EMEN1MAPT
SCHEMBL13206636 0.68 MEN1 (0.36) TRPM8ALDH1A1KMT2AMEN1MAPT
SCHEMBL2401467 0.68 TRPM8 (0.46) SLC6A2SLC6A4TRPM8ALDH1A1MAPT
SCHEMBL15405371 0.67 ALDH1A1 (0.37) ALDH1A1KMT2AKDM4EMEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020086181-A1 Organic electroluminescent device and preparation thereof ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE (KR) 2002-07-04 US claimed
EP-1725609-B1 CARBODIIMIDES COMPRISING THIOCARBAMIDE ACID ESTER GROUPS BASF SE (DE) 2008-05-21 EP disclosed
EP-1725609-A2 CARBODIIMIDES COMPRISING THIOCARBAMIDE ACID ESTER GROUPS BASF AKTIENGESELLSCHAFT (DE) 2006-11-29 EP disclosed
WO-2005087718-A2 CARBODIIMIDES COMPRISING THIOCARBAMIDE ACID ESTER GROUPS BASF AKTIENGESELLSCHAFT (DE) 2005-09-22 WO disclosed
US-6805976-B2 LUMINESCENT EFFICIENCY AND COLOR COORDINATES BASED ON A HIGH PURITY, SIMPLE IN SYNTHESIS; THERMAL STABILITY ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE (KR) 2004-10-19 US disclosed
US-20020086181-A1 Organic electroluminescent device and preparation thereof ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE (KR) 2002-07-04 US disclosed
EP-0795421-B1 Laser addressable thermal transfer imaging element and method of forming an image MINNESOTA MINING & MFG (US) 2002-07-03 EP disclosed
US-5708178-A Thermally stable electro-optic device and method LOCKHEED MARTIN CORPORATION (US) 1998-01-13 US disclosed
US-5695907-A Laser addressable thermal transfer imaging element and method MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-12-09 US disclosed
EP-0795421-A2 Laser addressable thermal transfer imaging element and method of forming an image MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-09-17 EP disclosed
US-5561733-A ACCEPTOR-DONOR-ACCEPTOR OR DONOR-ACCEPTOR-DONOR GUEST DIPOLE COMPOUNDS IN A TEMPERATURE-RESISTANCE POLYMER MATRIX LOCKHEAD MISSILES & SPACE COMPANY, INC. (US) 1996-10-01 US disclosed
EP-0000829-B1 PHOTOVOLTAIC ELEMENTS EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1982-01-06 EP disclosed
EP-0000829-A1 Photovoltaic elements EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1979-02-21 EP disclosed