Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 4/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.33 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4664967 | 0.82 | SLC6A2 (0.35) | SLC6A2SLC6A4CYP2D6TRPM8GRIN2D | |
| SCHEMBL9327532 | 0.80 | TDP1 (0.38) | POLBALDH1A1KMT2AMEN1ALOX5 | |
| Hydrochloric Acid SCHEMBL9326182 | 0.78 | TDP1 (0.37) | POLBALDH1A1KMT2AMEN1ALOX5 | |
| SCHEMBL9769958 | 0.75 | SMN1; SMN2 (0.37) | CYP2D6TRPM8POLBALDH1A1KMT2A | |
| SCHEMBL9779593 | 0.72 | PKM (0.41) | POLBALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL8388974 | 0.70 | POLB (0.37) | POLBALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL7034994 | 0.69 | SLC6A2 (0.35) | SLC6A2SLC6A4CYP2D6TRPM8GRIN2D | |
| SCHEMBL7034990 | 0.68 | SLC6A2 (0.34) | SLC6A2SLC6A4CYP2D6TRPM8ALDH1A1 | |
| SCHEMBL7765615 | 0.66 | POLB (0.39) | POLBALDH1A1KMT2AMEN1ALOX5 | |
| SCHEMBL8981966 | 0.65 | ALOX5 (0.49) | POLBALDH1A1KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0557305-B1 | (2-THIENYL) ALKYLAMINE DERIVATIVES HAVING NEUROPROTECTIVE PROPERTIES | ASTRA AB (SE) | 1997-06-11 | — | — | EP | disclosed |