Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 13/20 | 0.54 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | FABP3 | P05413 | 1/20 | 0.38 |
| ▸ | FABP4 | P15090 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14600273 | 0.93 | DHODH (0.46) | DHODHKEAP1NFE2L2MAPTTP53 | |
| SCHEMBL4666640 | 0.85 | DHODH (0.58) | DHODHKEAP1NFE2L2MAPTTP53 | |
| Hydrochloric Acid SCHEMBL4666221 | 0.84 | DHODH (0.57) | DHODHKEAP1NFE2L2MAPTTP53 | |
| SCHEMBL14600682 | 0.80 | DHODH (0.55) | DHODHKEAP1NFE2L2 | |
| SCHEMBL4668988 | 0.77 | DHODH (0.49) | DHODHKEAP1NFE2L2MAPTTP53 | |
| SCHEMBL5008553 | 0.77 | ADORA1 (0.59) | DHODHMAPTTP53 | |
| SCHEMBL14600673 | 0.76 | DHODH (0.47) | DHODHKEAP1NFE2L2MAPTTP53 | |
| SCHEMBL14600691 | 0.75 | DHODH (0.49) | DHODHKEAP1NFE2L2 | |
| SCHEMBL4666815 | 0.75 | ALDH1A1 (0.42) | KEAP1NFE2L2MAPTTP53FABP3 | |
| SCHEMBL14600727 | 0.75 | DHODH (0.55) | DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1928455-A1 | ANILINOPYRAZOLE DERIVATIVES USEFUL FOR THE TREATMENT OF DIABETES | Bayer Healthcare, LLC (US) | 2008-06-11 | — | — | EP | disclosed |
| WO-2007027842-A1 | ANILINOPYRAZOLE DERIVATIVES USEFUL FOR THE TREATMENT OF DIABETES | BAYER HEALTHCARE LLC (US) | 2007-03-08 | — | — | WO | disclosed |
| WO-2007027842-A1 | ANILINOPYRAZOLE DERIVATIVES USEFUL FOR THE TREATMENT OF DIABETES | BAYER HEALTHCARE LLC (US) | 2007-03-08 | — | — | WO | disclosed |