SCHEMBL4665336

SCHEMBL4665336

NC(=O)c1cccc(NC(=O)c2ccccc2)n1

nearest known ligand 0.74

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.74
MEN1 O00255 3/20 0.74
NPC1 O15118 5/20 0.57
RAB9A P51151 5/20 0.57
RXFP1 Q9HBX9 1/20 0.56
GRM5 P41594 4/20 0.54
ATM Q13315 1/20 0.52
KDM4E B2RXH2 1/20 0.50
LMNA P02545 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
CCNA2 P20248 1/20 0.49
CDK2 P24941 1/20 0.49
CCNA1 P78396 1/20 0.49
ADORA3 P0DMS8 1/20 0.49
ADORA1 P30542 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28937146 0.86 KMT2A (0.79) KMT2AMEN1NPC1RAB9ARXFP1
SCHEMBL821839 0.86 KMT2A (1.00) KMT2AMEN1NPC1RAB9ARXFP1
SCHEMBL15408966 0.84 KDM4E (0.54) KMT2AMEN1NPC1RAB9ARXFP1
SCHEMBL22673128 0.83 HSD17B10 (0.56) KMT2AMEN1NPC1RAB9ALMNA
SCHEMBL2664554 0.81 KMT2A (0.77) KMT2AMEN1NPC1RAB9ARXFP1
SCHEMBL28937132 0.81 KMT2A (0.70) KMT2AMEN1NPC1RAB9ARXFP1
SCHEMBL7798242 0.79 KDM4E (0.72) KMT2AMEN1RAB9ARXFP1GRM5
SCHEMBL23286796 0.78 KMT2A (0.77) KMT2AMEN1NPC1RAB9ARXFP1
SCHEMBL2664547 0.78 KMT2A (0.83) KMT2AMEN1NPC1RAB9ARXFP1
SCHEMBL9753586 0.78 RAB9A (0.88) KMT2AMEN1NPC1RAB9AGRM5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1913815-A1 PEST CONTROL COMPOSITION Mitsui Chemicals, Inc. (JP) 2008-04-23 EP disclosed