SCHEMBL22673128

SCHEMBL22673128

NC(=O)c1cccc(NC(=O)c2cccnc2)n1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.56
LMNA P02545 1/20 0.55
HIF1A Q16665 1/20 0.55
SIRT2 Q8IXJ6 2/20 0.54
F7 P08709 1/20 0.54
F3 P13726 1/20 0.54
SARM1 Q6SZW1 1/20 0.54
SIRT6 Q8N6T7 1/20 0.54
SIRT1 Q96EB6 1/20 0.54
SIRT3 Q9NTG7 1/20 0.54
SIRT5 Q9NXA8 1/20 0.54
SIRT4 Q9Y6E7 1/20 0.54
ROCK2 O75116 1/20 0.54
ROCK1 Q13464 1/20 0.54
SMN1; SMN2 Q16637 3/20 0.53
HDAC1 Q13547 2/20 0.52
HDAC3 O15379 1/20 0.52
HDAC2 Q92769 1/20 0.52
KCNK3 O14649 1/20 0.52
HTT P42858 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4665336 0.83 KMT2A (0.74) LMNASMN1; SMN2MEN1KMT2ANPC1
SCHEMBL1520345 0.81 HSD17B10 (0.65) HSD17B10KMT2ANPC1RAB9A
SCHEMBL23015808 0.78 PRKAB2 (0.58) HSD17B10LMNAHIF1AROCK2ROCK1
SCHEMBL6647475 0.78 SMN1; SMN2 (0.58) HSD17B10LMNAHIF1AROCK2ROCK1
SCHEMBL30909075 0.77 HTR1F (0.70) HSD17B10LMNAHIF1ASMN1; SMN2KMT2A
SCHEMBL2535079 0.77 HTR1F (0.70) HSD17B10LMNAHIF1ASMN1; SMN2KMT2A
SCHEMBL23488400 0.77 SMN1; SMN2 (0.68) HSD17B10LMNAHIF1ASIRT2F7
SCHEMBL6646471 0.76 RAB9A (0.70) LMNAHIF1AROCK2ROCK1SMN1; SMN2
SCHEMBL31414959 0.76 RAB9A (0.70) LMNAHIF1AROCK2ROCK1SMN1; SMN2
SCHEMBL28826507 0.75 RAB9A (0.57) HSD17B10LMNAHIF1ASMN1; SMN2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200360249-A1 AN ANTIMICROBIAL COMPOSITION CONOPCO INC DBA UNILEVER (US) 2020-11-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200360249-A1 AN ANTIMICROBIAL COMPOSITION PPOX, CUTA, LPO HSD17B10 1214/4885LMNA 4631/4885HIF1A 4181/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.