Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EED | O75530 | 2/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4665646 | 0.87 | OPRK1 (0.48) | EEDOPRD1OPRK1HTR1ASLC6A4 | |
| SCHEMBL4665484 | 0.79 | SLC6A2 (0.45) | EEDOPRD1OPRK1SLC6A4KMT2A | |
| SCHEMBL4663491 | 0.76 | SLC6A4 (0.47) | EEDOPRD1OPRK1HTR1ASLC6A4 | |
| SCHEMBL4664062 | 0.75 | OPRK1 (0.48) | EEDOPRD1OPRK1HTR1ASLC6A4 | |
| SCHEMBL4663475 | 0.73 | OPRD1 (0.39) | OPRD1OPRK1SLC6A4KMT2AMEN1 | |
| SCHEMBL4664178 | 0.72 | OPRK1 (0.41) | EEDOPRD1OPRK1SLC6A4KMT2A | |
| SCHEMBL4665351 | 0.71 | OPRK1 (0.45) | EEDOPRD1OPRK1SLC6A4KMT2A | |
| SCHEMBL5344908 | 0.71 | SLC6A4 (0.49) | EEDOPRD1OPRK1HTR1ASLC6A4 | |
| SCHEMBL4665319 | 0.71 | SLC6A4 (0.51) | EEDOPRD1OPRK1HTR1ASLC6A4 | |
| SCHEMBL4663539 | 0.71 | SLC6A4 (0.47) | EEDOPRD1OPRK1HTR1ASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1571140-B1 | C-substituted cyclohexylmethylamine derivatives | GRUENENTHAL GMBH (DE) | 2008-11-12 | — | — | EP | claimed |