SCHEMBL466574

SCHEMBL466574

OC[C@H]1N[C@H](CO)[C@@H](O)[C@@H]1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
GLA P06280 6/20 1.00
AGL P35573 3/20 1.00
GAA P10253 2/20 1.00
GBA1 P04062 2/20 1.00
GBA2 Q9HCG7 1/20 1.00
MGAM O43451 5/20 0.93
FUCA1 P04066 5/20 0.93
GANC Q8TET4 2/20 0.93

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19745374 1.00 GLA (1.00) GLAAGLGAAGBA1GBA2
SCHEMBL19557590 1.00 GLA (1.00) GLAAGLGAAGBA1GBA2
SCHEMBL15593220 1.00 GLA (1.00) GLAAGLGAAGBA1GBA2
SCHEMBL13317732 1.00 GLA (1.00) GLAAGLGAAGBA1GBA2
SCHEMBL10028909 1.00 GLA (1.00) GLAAGLGAAGBA1GBA2
SCHEMBL14268489 1.00 GLA (1.00) GLAAGLGAAGBA1GBA2
SCHEMBL4319863 1.00 GLA (1.00) GLAAGLGAAGBA1GBA2
SCHEMBL2435520 1.00 GLA (1.00) GLAAGLGAAGBA1GBA2
SCHEMBL466573 1.00 GLA (1.00) GLAAGLGAAGBA1GBA2
SCHEMBL13848041 1.00 GLA (1.00) GLAAGLGAAGBA1GBA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 318 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024102639-A1 N-ARYLPYRAZOLE NOD2 AGONISTS AS PROMOTERS OF IMMUNE CHECKPOINT INHIBITOR THERAPY THE SCRIPPS RESEARCH INSTITUTE (US) 2024-05-16 WO claimed
CN-116920617-A Preparation method of in-situ immobilized laccase polyvinylidene fluoride membrane 沈阳建筑大学 2023-10-24 CN claimed
WO-2023090761-A1 METHOD FOR ELECTROSPINNING OF HIGH-EFFICIENCY NANOFIBER AIR FILTER BY USING PVDF-G-POEM DOUBLE COMB COPOLYMER 주식회사 레몬 2023-05-25 WO claimed
US-20230058412-A1 Carbohydrate-Modified Particles and Particulate Formulations for Modulating an Immune Response NORTHWESTERN UNIVERSITY 2023-02-23 US claimed
US-20230038373-A1 STABILE CONJUGATE GLYKOS BIOMEDICAL OY (FI) 2023-02-09 US claimed
EP-3976233-A1 SEQUESTERING COMPOSITIONS AND MATERIALS Alliance for Sustainable Energy, LLC (US) 2022-04-06 EP claimed
CN-215646221-U Charge-discharge control circuit based on Type-c interface 深圳维普创新科技有限公司 2022-01-25 CN claimed
US-20210402002-A1 CONJUGATE GLYKOS BIOMEDICAL OY (FI) 2021-12-30 US claimed
US-20210205443-A1 Carbohydrate-Modified Particles and Particulate Formulations for Modulating an Immune Response NORTHWESTERN UNIVERSITY 2021-07-08 US claimed
WO-2021123506-A1 STABILE CONJUGATE GLYKOS BIOMEDICAL OY (FI) 2021-06-24 WO claimed
US-20020198225-A1 Administering a competitive inhibitor of the enzyme in an amount effective to enhance enzyme activtiy, selected from 2,5-dideoxy- 2,5-imino-D-mannitol, 3,4-diepi- alpha -homonojirimycin, 5-O- deoxyglactonojirimycin, calystegines MOUNT SINAI SCHOOL OF MEDICINE 2002-12-26 US claimed
US-20020156100-A1 1-deoxy-galactonojirimycin and related compounds used to treat fabry disease MOUNT SINAI SCHOOL OF MEDICINE 2002-10-24 US claimed
US-20020035072-A1 Administering reversible competitive inhibitor of enzyme in an amount effective to enhance activity of enzyme in cell MOUNT SINAI SCHOOL OF MEDICINE OF NEW YORK UNIVERSITY. 2002-03-21 US claimed
US-6274597-B1 ADMINISTERING 1-DEOXYGALACTONOJIRIMYCIN AND RELATED COMPOUNDS TO TREAT FABRY DISEASE MOUNT SINAI SCHOOL OF MEDICINE OF NEW YORK UNIVERSITY 2001-08-14 US claimed
EP-1083899-A1 METHOD OF ENHANCING LYSOSOMAL $g(a)-GALACTOSIDASE A Fan, Jian-Qiang (US) 2001-03-21 EP claimed
WO-1999062517-A1 METHOD OF ENHANCING LYSOSOMAL α-GALACTOSIDASE A FAN JIAN QIANG (US) 1999-12-09 WO claimed
EP-0561820-B1 CONTROL OF PARASITIC NEMATODES BRITISH TECH GROUP (GB) 1996-03-20 EP claimed
US-5376675-A Applying 2R,5R-dihydroxymethyl-3R,4R-dihydroxypyrrolidine BRITISH TECHNOLOGY GROUP LIMITED (GB) 1994-12-27 US claimed
EP-0561820-A1 CONTROL OF PARASITIC NEMATODES (A). BRITISH TECH GROUP (GB) 1993-09-29 EP claimed
WO-1992009202-A1 CONTROL OF PARASITIC NEMATODES (A) BRITISH TECHNOLOGY GROUP LTD (GB) 1992-06-11 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020035072-A1 Administering reversible competitive inhibitor of enzyme in an amount effective to enhance activity of enzyme in cell GAA, MAN2B1, IDE GLA 29/4885AGL 25/4885GAA 1/4885
US-20020198225-A1 Administering a competitive inhibitor of the enzyme in an amount effective to enhance enzyme activtiy, selected from 2,5-dideoxy- 2,5-imino-D-mannitol, 3,4-diepi- alpha -homonojirimycin, 5-O- deoxyglactonojirimycin, calystegines MAN2B1, GAA, MAN2A1 GLA 34/4885AGL 31/4885GAA 2/4885
US-20210402002-A1 CONJUGATE ST6GAL1, CSGALNACT1, FUT6 GLA 278/4885AGL 564/4885GAA 72/4885
US-20020156100-A1 1-deoxy-galactonojirimycin and related compounds used to treat fabry disease GAA, GALC, GLA GLA 3/4885AGL 189/4885GAA 1/4885
US-20230038373-A1 STABILE CONJUGATE CD2, TTL, DDOST GLA 536/4885AGL 308/4885GAA 283/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.