⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5358862 | 0.83 | ALDH1A1 (0.37) | — | |
| SCHEMBL14048182 | 0.79 | GFER (0.72) | — | |
| SCHEMBL1994985 | 0.77 | GFER (0.68) | — | |
| SCHEMBL8226214 | 0.75 | — | — | |
| SCHEMBL3482770 | 0.73 | CYP3A4 (1.00) | — | |
| SCHEMBL3482833 | 0.73 | GFER (1.00) | — | |
| SCHEMBL6362775 | 0.73 | CYP3A4 (1.00) | — | |
| 4,4'-Methylenedianiline SCHEMBL28001 | 0.73 | CYP3A4 (1.00) | — | |
| SCHEMBL8094139 | 0.73 | CYP3A4 (1.00) | — | |
| SCHEMBL1304762 | 0.73 | CYP3A4 (1.00) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 368 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118339165-A | Antibody-drug conjugates and methods of use thereof | R.P.谢勒技术有限责任公司 | 2024-07-12 | — | — | CN | claimed |
| EP-4392456-A2 | ANTIBODIES HAVING HUMANIZED FRAMEWORK REGIONS | R.P. Scherer Technologies, LLC (US) | 2024-07-03 | — | — | EP | claimed |
| EP-4392077-A2 | TUMOR-ASSOCIATED CALCIUM SIGNAL TRANSDUCER 2 (TACSTD2) ANTIBODY-MAYTANSINE CONJUGATES AND METHODS OF USE THEREOF | R.P. Scherer Technologies, LLC (US) | 2024-07-03 | — | — | EP | claimed |
| US-20240197907-A1 | Dual-Cleavage Ester Linkers for Antibody-Drug Conjugates | ARES CAPITAL CORPORATION, AS COLLATERAL AGENT | 2024-06-20 | — | — | US | claimed |
| EP-4377319-A2 | ANTIBODIES AND ANTIBODY CONJUGATES SPECIFIC FOR NECTIN-4 AND METHODS OF USE THEREOF | R.P. Scherer Technologies, LLC (US) | 2024-06-05 | — | — | EP | claimed |
| EP-4377320-A2 | ANTIBODY-DRUG CONJUGATES AND METHODS OF USE THEREOF | R.P. Scherer Technologies, LLC (US) | 2024-06-05 | — | — | EP | claimed |
| CN-118119644-A | Antibodies with humanized framework regions | R.P.谢勒技术有限责任公司 | 2024-05-31 | — | — | CN | claimed |
| CN-118076390-A | Tumor-associated calcium signal transduction factor 2 (TACSTD 2) antibody-maytansine conjugates and methods of use thereof | R.P.谢勒技术有限责任公司 | 2024-05-24 | — | — | CN | claimed |
| US-20240166693-A1 | METHODS AND COMPOUNDS FOR MODULATING MYOTONIC DYSTROPY 1 | Design Therapeutics, Inc. | 2024-05-23 | — | — | US | claimed |
| CN-118043328-A | Antibodies and antibody conjugates specific for NECTIN-4 and methods of use thereof | R·P·舍勒科技有限责任公司 | 2024-05-14 | — | — | CN | claimed |
| US-20030100559-A1 | Substituted polycyclic aryl and heteroaryl tertiary-heteroalkylamines useful for inhibiting cholesteryl ester transfer protein activity | G.D. SEARLE & CO. | 2003-05-29 | — | — | US | claimed |
| US-20030096818-A1 | Substituted polycyclic aryl and heteroaryl tertiary-heteroalkylamines useful for inhibiting cholesteryl ester transfer protein activity | G.D. SEARLE & CO. (US) | 2003-05-22 | — | — | US | claimed |
| US-20030087905-A1 | Substituted polycyclic aryl and heteroaryl tertiary-heteroalkylamines useful for inhibiting cholesteryl ester transfer protein activity | G.D. SEARLE & CO. | 2003-05-08 | — | — | US | claimed |
| US-20030083331-A1 | Substituted polycyclic aryl and heteroaryl tertiary-heteroalkylamines useful for inhibiting cholesteryl ester transfer protein activity | G.D. SEARLE & CO. (US) | 2003-05-01 | — | — | US | claimed |
| US-20030032644-A1 | Substituted polycyclic aryl and heteroaryl tertiary-heteroalkylamines useful for inhibiting cholesteryl ester transfer protein activity | G.D. SEARLE & CO. | 2003-02-13 | — | — | US | claimed |
| US-20020165232-A1 | Substituted N, N-disubstituted cycloalkyl aminoalcohol compounds useful for inhibiting cholesteryl ester transfer protein activity | SIKORSKI JAMES A (US) | 2002-11-07 | — | — | US | claimed |
| US-20020165231-A1 | Substituted N-heteroaryl-N-phenyl aminoalcohol compounds useful for inhibiting cholesteryl ester transfer protein activity | SIKORSKI JAMES A (US) | 2002-11-07 | — | — | US | claimed |
| WO-2001098291-A2 | 1,3-BIS-(SUBSTITUTED-PHENYL)-2-PROPEN-1-ONES AND THEIR USE TO TREAT VCAM-1 MEDIATED DISORDERS | ATHEROGENICS, INC. (US) | 2001-12-27 | — | — | WO | claimed |
| EP-1115693-A1 | SUBSTITUTED POLYCYCLIC ARYL AND HETEROARYL $i(TERTIARY)-HETEROALKYLAMINES USEFUL FOR INHIBITING CHOLESTERYL ESTER TRANSFER PROTEIN ACTIVITY | Monsanto Company (US) | 2001-07-18 | — | — | EP | claimed |
| WO-2000018721-A1 | SUBSTITUTED POLYCYCLIC ARYL AND HETEROARYL TERTIARY-HETEROALKYLAMINES USEFUL FOR INHIBITING CHOLESTERYL ESTER TRANSFER PROTEIN ACTIVITY | MONSANTO COMPANY (US) | 2000-04-06 | — | — | WO | claimed |