SCHEMBL4666032

SCHEMBL4666032

NC(=Cc1ccccc1)[n+]1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 1/20 0.40
KDM1A O60341 1/20 0.40
FBP1 P09467 3/20 0.38
ALDH1A1 P00352 1/20 0.38
TSHR P16473 1/20 0.38
AKR1C3 P42330 1/20 0.38
GRIN2D O15399 2/20 0.36
GRIN3B O60391 2/20 0.36
GRIN1 Q05586 2/20 0.36
GRIN2A Q12879 2/20 0.36
GRIN2B Q13224 2/20 0.36
GRIN2C Q14957 2/20 0.36
GRIN3A Q8TCU5 2/20 0.36
TAAR1 Q96RJ0 1/20 0.36
AKR1C1 Q04828 1/20 0.36
ESR1 P03372 1/20 0.36
CHAT P28329 1/20 0.34
CYP3A4 P08684 1/20 0.33
CYP2C9 P11712 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8625481 0.77 TSHR (0.40) KDM1AFBP1ALDH1A1TSHRAKR1C3
SCHEMBL6067750 0.72 GRIN2D (0.45) ALDH1A1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL9508726 0.71 ALDH1A1 (0.39) KDM1AFBP1ALDH1A1TSHRAKR1C3
SCHEMBL1377680 0.71 ALDH1A1 (0.48) MCL1FBP1ALDH1A1TSHRAKR1C3
SCHEMBL7044923 0.71 MCL1 (0.48) MCL1KDM1AFBP1ALDH1A1TSHR
SCHEMBL16432781 0.71 MCL1 (0.48) MCL1KDM1AFBP1ALDH1A1TSHR
SCHEMBL236283 0.71 MCL1 (0.48) MCL1KDM1AFBP1ALDH1A1TSHR
SCHEMBL859579 0.71 MCL1 (0.48) MCL1KDM1AFBP1ALDH1A1TSHR
SCHEMBL16432779 0.71 MCL1 (0.48) MCL1KDM1AFBP1ALDH1A1TSHR
SCHEMBL3635422 0.70 MEN1 (0.39) MCL1FBP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110730908-B Engineered cells expressing Prostate Specific Membrane Antigen (PSMA) or modified versions thereof and related methods 朱诺治疗学股份有限公司 2025-01-21 CN claimed
US-20230190796-A1 ENGINEERED CELLS EXPRESSING PROSTATE-SPECIFIC MEMBRANE ANTIGEN (PSMA) OR A MODIFIED FORM THEREOF AND RELATED METHODS JUNO THERAPEUTICS, INC. (US) 2023-06-22 US claimed
EP-3607319-A1 ENGINEERED CELLS EXPRESSING PROSTATE-SPECIFIC MEMBRANE ANTIGEN (PSMA) OR A MODIFIED FORM THEREOF AND RELATED METHODS Juno Therapeutics, Inc. (US) 2020-02-12 EP claimed
CN-110730908-A Engineered cells expressing Prostate Specific Membrane Antigen (PSMA) or modified forms thereof and related methods 朱诺治疗学股份有限公司 2020-01-24 CN claimed
WO-2018187791-A1 ENGINEERED CELLS EXPRESSING PROSTATE-SPECIFIC MEMBRANE ANTIGEN (PSMA) OR A MODIFIED FORM THEREOF AND RELATED METHODS JUNO THERAPEUTICS, INC (US) 2018-10-11 WO claimed
EP-1019722-B1 POLYMERIC FLUOROPHORES ENHANCED BY MOIETIES PROVIDING A HYDROPHOBIC AND CONFORMATIONALLY RESTRICTIVE MICROENVIRONMENT ABBOTT LAB (US) 2003-04-09 EP claimed
EP-1019722-A1 POLYMERIC FLUOROPHORES ENHANCED BY MOIETIES PROVIDING A HYDROPHOBIC AND CONFORMATIONALLY RESTRICTIVE MICROENVIRONMENT Abbott Laboratories (US) 2000-07-19 EP claimed
US-5834230-A Viscosity Probe MCGILL UNIVERSITY (CA) 1998-11-10 US claimed
WO-1997028447-A1 POLYMERIC FLUOROPHORES ENHANCED BY MOIETIES PROVIDING A HYDROPHOBIC AND CONFORMATIONALLY RESTRICTIVE MICROENVIRONMENT ABBOTT LABORATORIES (US) 1997-08-07 WO claimed
EP-4419206-B1 COMPOUNDS FOR THE TREATMENT OF MALARIA FUNDACIO INST DE BIOENGINYERIA DE CATALUNYA (ES) 2025-09-17 EP disclosed
CN-110730908-B Engineered cells expressing Prostate Specific Membrane Antigen (PSMA) or modified versions thereof and related methods 朱诺治疗学股份有限公司 2025-01-21 CN disclosed
US-20240415825-A1 COMPOUNDS FOR THE TREATMENT OF MALARIA Fundación Privada Instituto De Salud Global Barcelona (ES) 2024-12-19 US disclosed
US-12104214-B2 PSMA-based molecular-genetic reporter system THE JOHNS HOPKINS UNIVERSITY (US) 2024-10-01 US disclosed
EP-4419206-A1 COMPOUNDS FOR THE TREATMENT OF MALARIA Fundacio Institut de Bioenginyeria de Catalunya (ES) 2024-08-28 EP disclosed
US-5840859-A (Aminostyryl)pyridinium compounds for radiolabelling cell membranes RESEARCH CORPORATION TECHNOLOGIES, INC. (US) 1998-11-24 US disclosed
US-5834230-A Viscosity Probe MCGILL UNIVERSITY (CA) 1998-11-10 US disclosed
US-5834230-A Viscosity Probe MCGILL UNIVERSITY (CA) 1998-11-10 US disclosed
WO-1997028447-A1 POLYMERIC FLUOROPHORES ENHANCED BY MOIETIES PROVIDING A HYDROPHOBIC AND CONFORMATIONALLY RESTRICTIVE MICROENVIRONMENT ABBOTT LABORATORIES (US) 1997-08-07 WO disclosed
WO-1997028447-A1 POLYMERIC FLUOROPHORES ENHANCED BY MOIETIES PROVIDING A HYDROPHOBIC AND CONFORMATIONALLY RESTRICTIVE MICROENVIRONMENT ABBOTT LABORATORIES (US) 1997-08-07 WO disclosed
WO-1997002246-A1 (AMINOSTYRYL)PYRIDINIUM COMPOUNDS FOR RADIOLABELLING CELL MEMBRANES RESEARCH CORPORATION TECHNOLOGIES, INC. (US) 1997-01-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240415825-A1 COMPOUNDS FOR THE TREATMENT OF MALARIA ABAT, GLS2, CPS1 MCL1 1105/4885KDM1A 3978/4885FBP1 2070/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.