Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | CHAT | P28329 | 2/20 | 0.37 |
| ▸ | FBP1 | P09467 | 3/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4666032 | 0.77 | MCL1 (0.40) | TSHRALDH1A1AKR1C3AKR1C1ESR1 | |
| SCHEMBL1377680 | 0.74 | ALDH1A1 (0.48) | TSHRALDH1A1AKR1C3AKR1C1ESR1 | |
| SCHEMBL9508726 | 0.74 | ALDH1A1 (0.39) | TSHRALDH1A1AKR1C3AKR1C1ESR1 | |
| Hydrochloric Acid SCHEMBL10696032 | 0.73 | ALDH1A1 (0.47) | TSHRALDH1A1AKR1C3AKR1C1KDM1A | |
| SCHEMBL8607275 | 0.73 | CHAT (0.39) | TSHRALDH1A1AKR1C3AKR1C1ESR1 | |
| SCHEMBL3315076 | 0.71 | AKR1C3 (0.50) | TSHRALDH1A1AKR1C3AKR1C1KDM1A | |
| SCHEMBL9015136 | 0.71 | FBP1 (0.38) | TSHRALDH1A1AKR1C3AKR1C1ESR1 | |
| Hydrochloric Acid SCHEMBL9052839 | 0.71 | CHAT (0.38) | TSHRALDH1A1AKR1C3AKR1C1ESR1 | |
| SCHEMBL29253620 | 0.68 | ALDH1A1 (0.50) | TSHRALDH1A1AKR1C3AKR1C1ESR1 | |
| SCHEMBL131223 | 0.68 | MAOB (0.53) | TSHRALDH1A1AKR1C3AKR1C1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5830623-A | Pattern lithography method | KABUSHIKI KAISHA TOSHIBA (JP) | 1998-11-03 | — | — | US | disclosed |