Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 5/20 | 0.66 |
| ▸ | UQCRB | P14927 | 1/20 | 0.56 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.56 |
| ▸ | CLK1 | P49759 | 1/20 | 0.56 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.56 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.56 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.55 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 2/20 | 0.55 |
| ▸ | CA2 | P00918 | 2/20 | 0.55 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | USP7 | Q93009 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL518114 | 0.94 | CA1 (0.61) | KIF11UQCRBCA1CA2KEAP1 | |
| SCHEMBL19227700 | 0.89 | LMNA (0.57) | KIF11UQCRBDYRK1BCLK1DYRK1A | |
| SCHEMBL31041151 | 0.89 | KIF11 (0.79) | KIF11DYRK1AHSD17B1HSD17B2CA1 | |
| Lithium SCHEMBL31041154 | 0.87 | KIF11 (0.76) | KIF11DYRK1AHSD17B1HSD17B2CA1 | |
| SCHEMBL12054668 | 0.82 | KEAP1 (0.75) | KIF11CA1CA2KEAP1HPGD | |
| SCHEMBL21254711 | 0.81 | KIF11 (0.68) | KIF11DYRK1AHSD17B1HSD17B2CA1 | |
| SCHEMBL873846 | 0.81 | KEAP1 (0.75) | KIF11UQCRBCA1CA2KEAP1 | |
| SCHEMBL4661398 | 0.81 | KIF11 (0.68) | KIF11DYRK1AHSD17B1HSD17B2CA1 | |
| SCHEMBL15771505 | 0.80 | KIF11 (0.62) | KIF11HSD17B1HSD17B2CA1CA2 | |
| SCHEMBL2497654 | 0.79 | KIF11 (0.66) | KIF11DYRK1AHSD17B1HSD17B2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1193250-B1 | PHENYL SULFAMATE DERIVATIVES | TEIKOKU HORMONE MFG CO LTD (JP) | 2008-06-04 | — | — | EP | disclosed |
| US-6762205-B1 | STEROID SULFATASE INHIBITORS WITHOUT ESTROGENIC SIDE EFFECT ACTION | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 2004-07-13 | — | — | US | disclosed |
| EP-1193250-A1 | PHENYL SULFAMATE DERIVATIVES | Teikoku Hormone Mfg. Co., Ltd. (JP) | 2002-04-03 | — | — | EP | disclosed |