Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | KIT | P10721 | 1/20 | 0.45 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.45 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.45 |
| ▸ | BACE1 | P56817 | 1/20 | 0.45 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.45 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TNNI3K | Q59H18 | 2/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.43 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4665695 | 0.92 | CYP1A2 (0.47) | MAPTBACE1ALDH1A1TNNI3KSCN9A | |
| SCHEMBL4667473 | 0.86 | MEN1 (0.51) | MAPTALDH1A1LMNATNNI3KKMT2A | |
| SCHEMBL4666195 | 0.85 | TNNI3K (0.50) | MAPTKITPTPN2PTPN1PTPN5 | |
| SCHEMBL4666141 | 0.85 | TNNI3K (0.49) | MAPTPGRPTPN2PTPN1PTPN5 | |
| SCHEMBL4666155 | 0.81 | CYP1A2 (0.48) | BACE1ALDH1A1LMNATNNI3KCYP1A2 | |
| SCHEMBL4663833 | 0.80 | CYP1A2 (0.47) | PGRPTPN2PTPN1PTPN5HSPD1 | |
| SCHEMBL4665802 | 0.77 | CYP1A2 (0.50) | KITALDH1A1LMNACYP1A2CYP3A4 | |
| SCHEMBL4665837 | 0.77 | SLC22A12 (0.50) | PTPN2PTPN1PTPN5HSPD1HSPE1 | |
| SCHEMBL15870338 | 0.76 | CCNT1 (0.65) | MAPTALDH1A1KMT2AMEN1CCNT1 | |
| SCHEMBL4664355 | 0.73 | CYP1A2 (0.46) | BACE1ALDH1A1LMNATNNI3KCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080242681-A1 | N-4-(6-(Hetero)Aryl-Pyrimidin-4-Ylaminophenyl)-Benzenesulfonamides as Kinase Inhibitors | ALTANA PHARMA AG (DE) | 2008-10-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080242681-A1 | N-4-(6-(Hetero)Aryl-Pyrimidin-4-Ylaminophenyl)-Benzenesulfonamides as Kinase Inhibitors | MAP3K19, MAP3K6, MAP3K20 | KMO 915/4885MAPT 4521/4885PGR 828/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.