Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 5/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | TNNI3K | Q59H18 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CDK9 | P50750 | 9/20 | 0.43 |
| ▸ | CCNT1 | O60563 | 8/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.41 |
| ▸ | CDK1 | P06493 | 2/20 | 0.41 |
| ▸ | CDK4 | P11802 | 2/20 | 0.41 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4666163 | 0.86 | ALDH1A1 (0.42) | CYP1A2CYP2D6CYP2C19CYP3A4CLK4 | |
| SCHEMBL5652786 | 0.85 | USP2 (0.61) | CYP1A2CYP2D6CYP2C19CLK4ALDH1A1 | |
| SCHEMBL4667473 | 0.85 | MEN1 (0.51) | CYP1A2CYP2D6CYP2C19CYP3A4CLK4 | |
| SCHEMBL4666195 | 0.78 | TNNI3K (0.50) | CYP1A2CYP2D6CYP2C19CYP3A4CLK4 | |
| SCHEMBL4665695 | 0.76 | CYP1A2 (0.47) | CYP1A2CYP2D6CYP2C19CYP3A4CLK4 | |
| SCHEMBL15870338 | 0.74 | CCNT1 (0.65) | ALDH1A1CDK9CCNT1USP2 | |
| SCHEMBL4666159 | 0.73 | KMO (0.48) | CYP1A2CYP2D6CYP2C19CYP3A4ALDH1A1 | |
| SCHEMBL4663808 | 0.72 | ALDH1A1 (0.54) | CYP1A2CYP2D6CYP2C19CYP3A4CLK4 | |
| SCHEMBL4666141 | 0.72 | TNNI3K (0.49) | CYP1A2CYP2D6CYP2C19CYP3A4CLK4 | |
| SCHEMBL4666121 | 0.72 | MEN1 (0.45) | CYP1A2CYP2D6CYP2C19CYP3A4CLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080242681-A1 | N-4-(6-(Hetero)Aryl-Pyrimidin-4-Ylaminophenyl)-Benzenesulfonamides as Kinase Inhibitors | ALTANA PHARMA AG (DE) | 2008-10-02 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080242681-A1 | N-4-(6-(Hetero)Aryl-Pyrimidin-4-Ylaminophenyl)-Benzenesulfonamides as Kinase Inhibitors | MAP3K19, MAP3K6, MAP3K20 | CYP1A2 1215/4885CYP2D6 646/4885CYP2C19 961/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.