Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 14/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.47 |
| ▸ | SLC22A8 | Q8TCC7 | 2/20 | 0.47 |
| ▸ | SLC22A11 | Q9NSA0 | 2/20 | 0.47 |
| ▸ | PTPN2 | P17706 | 3/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.47 |
| ▸ | PTPN5 | P54829 | 3/20 | 0.47 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.44 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.44 |
| ▸ | RORA | P35398 | 1/20 | 0.43 |
| ▸ | RORC | P51449 | 1/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4663833 | 0.87 | CYP1A2 (0.47) | CYP2C9PTPN2PTPN1PTPN5CYP3A4 | |
| SCHEMBL4665802 | 0.82 | CYP1A2 (0.50) | CYP2C9CYP3A4CYP1A2RORC | |
| SCHEMBL4666155 | 0.82 | CYP1A2 (0.48) | CYP2C9SLC40A1CYP3A4CYP1A2 | |
| SCHEMBL4664312 | 0.79 | SLC22A12 (0.52) | SLC22A12CYP2C9CYP3A4CYP1A2 | |
| SCHEMBL4667473 | 0.79 | MEN1 (0.51) | CYP2C9CYP3A4CYP1A2 | |
| SCHEMBL4666195 | 0.78 | TNNI3K (0.50) | CYP2C9PTPN2PTPN1PTPN5CYP3A4 | |
| SCHEMBL4666141 | 0.78 | TNNI3K (0.49) | CYP2C9PTPN2PTPN1PTPN5CYP3A4 | |
| SCHEMBL4666159 | 0.77 | KMO (0.48) | CYP2C9PTPN2PTPN1PTPN5CYP3A4 | |
| SCHEMBL4665695 | 0.76 | CYP1A2 (0.47) | CYP2C9CYP3A4CYP1A2 | |
| SCHEMBL4665768 | 0.75 | TNNI3K (0.46) | CYP3A4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080242681-A1 | N-4-(6-(Hetero)Aryl-Pyrimidin-4-Ylaminophenyl)-Benzenesulfonamides as Kinase Inhibitors | ALTANA PHARMA AG (DE) | 2008-10-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080242681-A1 | N-4-(6-(Hetero)Aryl-Pyrimidin-4-Ylaminophenyl)-Benzenesulfonamides as Kinase Inhibitors | MAP3K19, MAP3K6, MAP3K20 | SLC22A12 4353/4885CYP2C9 1047/4885SLC22A6 3766/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.