Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 10/20 | 0.55 |
| ▸ | STS | P08842 | 9/20 | 0.55 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.37 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30676130 | 0.84 | VCAM1 (0.55) | VCAM1ALDH1A1LMNAPTGS1PTGS2 | |
| SCHEMBL26926315 | 0.84 | VCAM1 (0.55) | VCAM1ALDH1A1LMNAPTGS1PTGS2 | |
| SCHEMBL4667754 | 0.82 | STS (0.67) | CYP19A1STSVCAM1CA2CA1 | |
| SCHEMBL4667798 | 0.81 | CA1 (0.54) | CYP19A1STSCA2CA1CA9 | |
| SCHEMBL4665412 | 0.80 | CYP19A1 (0.56) | CYP19A1STSCA2PTGS1PTGS2 | |
| SCHEMBL4665389 | 0.80 | STS (0.50) | CYP19A1STSVCAM1CA2CA1 | |
| SCHEMBL30676035 | 0.75 | MAPT (0.51) | CYP19A1VCAM1ALDH1A1LMNAPTGS2 | |
| SCHEMBL26926327 | 0.75 | MAPT (0.51) | CYP19A1VCAM1ALDH1A1LMNAPTGS2 | |
| SCHEMBL8140554 | 0.75 | VCAM1 (0.60) | VCAM1ALDH1A1LMNAPTGS2 | |
| SCHEMBL4666136 | 0.74 | CA1 (0.52) | CYP19A1STSVCAM1CA2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1193250-B1 | PHENYL SULFAMATE DERIVATIVES | TEIKOKU HORMONE MFG CO LTD (JP) | 2008-06-04 | — | — | EP | disclosed |
| US-6762205-B1 | STEROID SULFATASE INHIBITORS WITHOUT ESTROGENIC SIDE EFFECT ACTION | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 2004-07-13 | — | — | US | disclosed |
| EP-1193250-A1 | PHENYL SULFAMATE DERIVATIVES | Teikoku Hormone Mfg. Co., Ltd. (JP) | 2002-04-03 | — | — | EP | disclosed |