Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 9/20 | 0.54 |
| ▸ | CA2 | P00918 | 9/20 | 0.54 |
| ▸ | CA9 | Q16790 | 8/20 | 0.54 |
| ▸ | CA12 | O43570 | 6/20 | 0.51 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.51 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.45 |
| ▸ | STS | P08842 | 5/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.44 |
| ▸ | CA3 | P07451 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA6 | P23280 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.44 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.39 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4666173 | 0.81 | CYP19A1 (0.55) | CA1CA2CA9PDE7ASTS | |
| SCHEMBL4667783 | 0.80 | CA1 (0.56) | CA1CA2CA9CA12STS | |
| SCHEMBL4667729 | 0.77 | CA2 (0.89) | CA1CA2CA9CA12CA14 | |
| SCHEMBL16712983 | 0.73 | ESR2 (0.56) | CA1CA2CA9CA12CA14 | |
| SCHEMBL11834351 | 0.73 | HSD17B10 (0.53) | PDE7AHSD17B10 | |
| SCHEMBL27565484 | 0.72 | CA2 (0.78) | CA1CA2CA9CA12CA14 | |
| SCHEMBL3519559 | 0.71 | CA2 (1.00) | CA1CA2CA9CA12CA14 | |
| SCHEMBL4667738 | 0.70 | CA2 (0.64) | CA1CA2CA9CA12CA14 | |
| SCHEMBL27581730 | 0.69 | PDE7A (0.58) | CA1CA2CA9CA12CA14 | |
| SCHEMBL10221069 | 0.68 | CA1 (0.76) | CA1CA2CA9CA12STS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1193250-B1 | PHENYL SULFAMATE DERIVATIVES | TEIKOKU HORMONE MFG CO LTD (JP) | 2008-06-04 | — | — | EP | disclosed |
| US-6762205-B1 | STEROID SULFATASE INHIBITORS WITHOUT ESTROGENIC SIDE EFFECT ACTION | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 2004-07-13 | — | — | US | disclosed |
| EP-1193250-A1 | PHENYL SULFAMATE DERIVATIVES | Teikoku Hormone Mfg. Co., Ltd. (JP) | 2002-04-03 | — | — | EP | disclosed |