Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 1/20 | 0.46 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | HTR5A | P47898 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | MPL | P40238 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16559357 | 0.76 | SRD5A1 (0.54) | TYMSSRD5A1CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL30538 | 0.74 | SRD5A1 (0.53) | TYMSSRD5A1CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL29689945 | 0.74 | SRD5A1 (0.53) | TYMSSRD5A1CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL20205853 | 0.74 | SRD5A1 (0.41) | TYMSSRD5A1CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL28081477 | 0.72 | DRD2 (0.46) | TYMSSRD5A1CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL15395880 | 0.71 | SRD5A1 (0.42) | TYMSSRD5A1CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL4161778 | 0.71 | CYP19A1 (0.43) | TYMSSRD5A1CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL28633125 | 0.71 | NOTUM (0.43) | DRD2KDM4EALDH1A1NOTUMGRM5 | |
| SCHEMBL25254802 | 0.69 | LMNA (0.49) | TYMSSRD5A1CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL26404131 | 0.69 | LMNA (0.49) | TYMSSRD5A1CYP19A1CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1982595-A1 | Insecticidal derivatives of substituted aminoheterocycles | Bayer CropScience AG (DE) | 2008-10-22 | — | — | EP | disclosed |
| EP-1977646-A1 | Insecticidal hydroxyethyl thlourea derivatives | Bayer CropScience AG (DE) | 2008-10-08 | — | — | EP | disclosed |