SCHEMBL20205853

SCHEMBL20205853

N/N=C1\CCc2c(F)cccc21

nearest known ligand 0.41

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SRD5A1 P18405 1/20 0.41
TYMS P04818 1/20 0.40
DRD2 P14416 2/20 0.40
DRD3 P35462 2/20 0.40
CYP19A1 P11511 2/20 0.39
CYP11B1 P15538 1/20 0.39
CYP11B2 P19099 1/20 0.39
NOS3 P29474 1/20 0.33
NOS2 P35228 1/20 0.33
HTR1A P08908 3/20 0.33
HTR7 P34969 3/20 0.33
MAPK1 P28482 1/20 0.33
HTR5A P47898 2/20 0.31
NOTUM Q6P988 1/20 0.30
LMNA P02545 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25254802 0.81 LMNA (0.49) SRD5A1TYMSDRD2DRD3CYP19A1
SCHEMBL26404131 0.81 LMNA (0.49) SRD5A1TYMSDRD2DRD3CYP19A1
SCHEMBL27873730 0.77 SRD5A1 (0.39) SRD5A1TYMSDRD2DRD3CYP19A1
SCHEMBL7897372 0.77 SRD5A1 (0.39) SRD5A1TYMSDRD2DRD3CYP19A1
SCHEMBL159742 0.77 SRD5A1 (0.39) SRD5A1TYMSDRD2DRD3CYP19A1
SCHEMBL4666252 0.74 TYMS (0.46) SRD5A1TYMSDRD2DRD3CYP19A1
SCHEMBL20205516 0.73 DRD2 (0.44) DRD2DRD3CYP19A1LMNA
SCHEMBL20205644 0.72 CYP19A1 (0.37) CYP19A1
SCHEMBL16559357 0.71 SRD5A1 (0.54) SRD5A1TYMSDRD2CYP19A1CYP11B1
SCHEMBL29690150 0.71 GPR3 (0.45) SRD5A1TYMSCYP19A1CYP11B1CYP11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11225470-B2 Tetrazolinone compounds and its use as pest control agents SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2022-01-18 US disclosed
EP-3544973-B1 TETRAZOLINONE COMPOUNDS AND ITS USE AS PEST CONTROL AGENTS SUMITOMO CHEMICAL CO (JP) 2021-07-28 EP disclosed
WO-2018097318-A1 TETRAZOLINONE COMPOUNDS AND ITS USE AS PEST CONTROL AGENTS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-05-31 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11225470-B2 Tetrazolinone compounds and its use as pest control agents CYC1, MT-CO1, CTRL SRD5A1 860/4885TYMS 3358/4885DRD2 2135/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.