Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 1/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA6 | P23280 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.44 |
| ▸ | VHL | P40337 | 1/20 | 0.39 |
| ▸ | ELOC | Q15369 | 1/20 | 0.39 |
| ▸ | ELOB | Q15370 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6364651 | 0.85 | MAOB (0.40) | TSHRTRPA1 | |
| Formic Acid SCHEMBL11392898 | 0.82 | TSHR (0.50) | PRSS1PRSS2PRSS3TSHRCA1 | |
| SCHEMBL30097737 | 0.80 | MAOB (0.52) | PRSS1PRSS2PRSS3TSHRCA1 | |
| SCHEMBL24197114 | 0.79 | CA2 (0.54) | TSHRCA1CA2CA12CA4 | |
| SCHEMBL41775 | 0.78 | TSHR (0.67) | PRSS1PRSS2PRSS3TSHRCA1 | |
| SCHEMBL105690 | 0.78 | ESR1 (0.52) | CA1CA2CA12CA4CA5A | |
| SCHEMBL2320498 | 0.77 | CHKA (0.41) | PRSS1PRSS2PRSS3TSHRCA1 | |
| SCHEMBL3392101 | 0.77 | HRH3 (0.43) | TSHRCA1CA2CA12CA9 | |
| SCHEMBL3496268 | 0.76 | ALDH1A1 (0.52) | PRSS1PRSS2PRSS3TSHRCA1 | |
| SCHEMBL1124751 | 0.76 | ALDH5A1 (0.52) | TSHRCA1CA2CA12CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633336-A4 | IMMUNOSUPPRESSANT COMPOUNDS AND COMPOSITIONS | IRM LLC (BM) | 2008-10-29 | — | — | EP | disclosed |
| EP-1633336-A2 | IMMUNOSUPPRESSANT COMPOUNDS AND COMPOSITIONS | IRM LLC (BM) | 2006-03-15 | — | — | EP | disclosed |
| WO-2004103306-A2 | IMMUNOSUPPRESSANT COMPOUNDS AND COMPOSITIONS | IRM LLC (BM) | 2004-12-02 | — | — | WO | disclosed |