Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.37 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CFTR | P13569 | 2/20 | 0.36 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.36 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.35 |
| ▸ | WNT3A | P56704 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.35 |
| ▸ | GABRP | O00591 | 1/20 | 0.35 |
| ▸ | GABRD | O14764 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4132050 | 0.86 | PTGDR2 (0.40) | ALDH1A1ATMMEN1KMT2ANPC1 | |
| SCHEMBL4137011 | 0.82 | SIRT2 (0.40) | ALDH1A1ATMMEN1KMT2ANPC1 | |
| SCHEMBL4140717 | 0.78 | PTGDR2 (0.42) | GPR84MEN1KMT2ANPC1RAB9A | |
| SCHEMBL4294902 | 0.77 | ADAM17 (0.43) | NPC1RAB9ACFTRCTNNB1WNT3A | |
| SCHEMBL4122099 | 0.74 | PTGDR2 (0.39) | NR4A2CREBBPCFTRADAM17GABRP | |
| SCHEMBL3767352 | 0.67 | CFTR (0.63) | ALDH1A1ATMGPR84NR4A2CREBBP | |
| SCHEMBL3122183 | 0.67 | ALDH1A1 (0.67) | ALDH1A1ATMGPR84NR4A2CREBBP | |
| SCHEMBL4122132 | 0.66 | IGF1R (0.41) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL117198 | 0.62 | ALDH1A1 (1.00) | ALDH1A1ATMGPR84NR4A2CREBBP | |
| SCHEMBL29544426 | 0.62 | ALDH1A1 (1.00) | ALDH1A1ATMGPR84NR4A2CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1934192-A1 | THIAZOLINONES AND OXAZOLINONES AND THEIR USE AS PTP1B INHIBITORS | Torrent Pharmaceuticals Ltd (IN) | 2008-06-25 | — | — | EP | disclosed |
| WO-2007032028-A1 | THIAZOLINONES AND OXAZOLINONES AND THEIR USE AS PTP1B INHIBITORS | TORRENT PHARMACEUTICALS LTD. (IN) | 2007-03-22 | — | — | WO | disclosed |