Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 2/20 | 0.57 |
| ▸ | ADORA1 | P30542 | 13/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14600184 | 0.89 | ADORA1 (0.49) | GFERADORA1ADORA3KDM4CMEN1 | |
| SCHEMBL4793978 | 0.88 | DHODH (0.47) | GFERADORA1KDM4CMAPTSMN1; SMN2 | |
| SCHEMBL4667612 | 0.86 | GFER (0.44) | GFERADORA1KDM4CLMNAKMT2A | |
| SCHEMBL4666768 | 0.86 | ADORA1 (0.45) | GFERADORA1KDM4CLMNAMAPT | |
| SCHEMBL5005161 | 0.81 | GFER (0.80) | GFERADORA1KMT2AMAPTPOLB | |
| SCHEMBL4665871 | 0.81 | RAF1 (0.46) | ADORA1 | |
| SCHEMBL6341693 | 0.79 | GFER (0.63) | GFERADORA1ADORA3MEN1LMNA | |
| SCHEMBL5096109 | 0.78 | GFER (0.57) | GFERADORA1ADORA3LMNAKMT2A | |
| SCHEMBL5008452 | 0.78 | GFER (0.56) | GFERADORA1ADORA3LMNAKMT2A | |
| SCHEMBL8354329 | 0.76 | GFER (0.49) | GFERADORA1MEN1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1928455-A1 | ANILINOPYRAZOLE DERIVATIVES USEFUL FOR THE TREATMENT OF DIABETES | Bayer Healthcare, LLC (US) | 2008-06-11 | — | — | EP | disclosed |
| WO-2007027842-A1 | ANILINOPYRAZOLE DERIVATIVES USEFUL FOR THE TREATMENT OF DIABETES | BAYER HEALTHCARE LLC (US) | 2007-03-08 | — | — | WO | disclosed |
| WO-2007027842-A1 | ANILINOPYRAZOLE DERIVATIVES USEFUL FOR THE TREATMENT OF DIABETES | BAYER HEALTHCARE LLC (US) | 2007-03-08 | — | — | WO | disclosed |