Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | DHODH | Q02127 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 6/20 | 0.40 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.40 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4793978 | 0.89 | DHODH (0.47) | GFERDHODHMAPTADORA1KDM4C | |
| SCHEMBL4666768 | 0.88 | ADORA1 (0.45) | GFERDHODHMAPTKDM4EHTT | |
| SCHEMBL4667080 | 0.86 | GFER (0.57) | GFERMAPTADORA1KDM4CLMNA | |
| SCHEMBL14600212 | 0.81 | KDM4C (0.38) | DHODHMAPTKDM4EADORA1P2RX7 | |
| SCHEMBL14600184 | 0.75 | ADORA1 (0.49) | GFERMAPTADORA1KDM4CLMNA | |
| SCHEMBL14600217 | 0.74 | MAPK14 (0.50) | GFERMAPTADORA1 | |
| SCHEMBL5008506 | 0.74 | MAPK14 (0.58) | ADORA1P2RY4 | |
| SCHEMBL6342122 | 0.73 | GFER (0.53) | GFERMAPTHTTFTOALDH1A1 | |
| SCHEMBL14600238 | 0.72 | MAPK14 (0.53) | — | |
| SCHEMBL6351819 | 0.72 | GFER (0.49) | GFERMAPTHTTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1928455-A1 | ANILINOPYRAZOLE DERIVATIVES USEFUL FOR THE TREATMENT OF DIABETES | Bayer Healthcare, LLC (US) | 2008-06-11 | — | — | EP | disclosed |
| WO-2007027842-A1 | ANILINOPYRAZOLE DERIVATIVES USEFUL FOR THE TREATMENT OF DIABETES | BAYER HEALTHCARE LLC (US) | 2007-03-08 | — | — | WO | disclosed |