Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 11/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4133059 | 0.81 | KMT2A (0.44) | ALOX5KMT2AMAPTALDH1A1GLA | |
| SCHEMBL4128994 | 0.77 | ALOX5 (0.40) | ALOX5KMT2AMAPTALDH1A1GLA | |
| SCHEMBL4128997 | 0.77 | ALOX5 (0.40) | ALOX5KMT2AMAPTALDH1A1GLA | |
| Acetic Acid SCHEMBL4129777 | 0.76 | ALOX5 (0.39) | ALOX5KMT2AMAPTALDH1A1GLA | |
| Acetic Acid SCHEMBL4143413 | 0.69 | ALDH1A1 (0.40) | ALOX5KMT2AMAPTALDH1A1GLA | |
| Acetic Acid SCHEMBL4669507 | 0.69 | ALDH1A1 (0.40) | ALOX5KMT2AMAPTALDH1A1GLA | |
| SCHEMBL6263688 | 0.65 | ALOX5 (0.55) | ALOX5KMT2AMAPTALDH1A1POLB | |
| SCHEMBL6263665 | 0.64 | ALOX5 (0.58) | ALOX5KMT2AMAPTALDH1A1L3MBTL1 | |
| Propionic Acid SCHEMBL4133346 | 0.63 | KMT2A (0.41) | ALOX5KMT2AMAPTALDH1A1GLA | |
| SCHEMBL29801693 | 0.63 | PRKCB (0.50) | ALOX5KMT2AMAPTPOLBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1934192-A1 | THIAZOLINONES AND OXAZOLINONES AND THEIR USE AS PTP1B INHIBITORS | Torrent Pharmaceuticals Ltd (IN) | 2008-06-25 | — | — | EP | disclosed |
| WO-2007032028-A1 | THIAZOLINONES AND OXAZOLINONES AND THEIR USE AS PTP1B INHIBITORS | TORRENT PHARMACEUTICALS LTD. (IN) | 2007-03-22 | — | — | WO | disclosed |