Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ACP3 | P15309 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | SSTR4 | P31391 | 2/20 | 0.35 |
| ▸ | GHSR | Q92847 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CHAT | P28329 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7192329 | 0.84 | ALDH1A1 (0.38) | KIF11ALDH1A1HSD17B10HPGDTSHR | |
| SCHEMBL24776438 | 0.80 | ALDH1A1 (0.39) | KIF11ALDH1A1HSD17B10HPGDTSHR | |
| SCHEMBL1780460 | 0.80 | ALDH1A1 (0.39) | KIF11ALDH1A1HSD17B10HPGDTSHR | |
| Hydrochloric Acid SCHEMBL7600295 | 0.79 | ALDH1A1 (0.38) | KIF11ALDH1A1HSD17B10HPGDTSHR | |
| SCHEMBL434166 | 0.77 | GABRA1 (0.38) | ALDH1A1TSHRCYP3A4CA2 | |
| SCHEMBL20013957 | 0.76 | ALDH1A1 (0.41) | KIF11ALDH1A1HSD17B10HPGDTSHR | |
| SCHEMBL19443085 | 0.76 | ALDH1A1 (0.41) | KIF11ALDH1A1HSD17B10HPGDTSHR | |
| SCHEMBL586805 | 0.76 | ALDH1A1 (0.41) | KIF11ALDH1A1HSD17B10HPGDTSHR | |
| SCHEMBL1321899 | 0.75 | ALDH1A1 (0.44) | KIF11ALDH1A1HSD17B10HPGDTSHR | |
| SCHEMBL3681420 | 0.75 | ALDH1A1 (0.44) | KIF11ALDH1A1HSD17B10HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1985612-A1 | Arymethylen substituted N-Acyl-gamma-aminoalcohols | Bayer Schering Pharma Aktiengesellschaft (DE) | 2008-10-29 | — | — | EP | disclosed |