SCHEMBL434166

SCHEMBL434166

Cc1ccccc1C(C)(N)CCO

nearest known ligand 0.38

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.38
GABRB2 P47870 1/20 0.38
CASR P41180 1/20 0.37
TSHR P16473 2/20 0.33
TDP1 Q9NUW8 2/20 0.33
ALDH1A1 P00352 1/20 0.33
ACHE P22303 1/20 0.33
CTNNB1 P35222 1/20 0.33
WNT3A P56704 1/20 0.33
TAAR1 Q96RJ0 2/20 0.32
SLC6A2 P23975 1/20 0.32
L3MBTL1 Q9Y468 2/20 0.32
CHRM3 P20309 2/20 0.32
CYP3A4 P08684 1/20 0.31
ATM Q13315 2/20 0.30
CA2 P00918 1/20 0.30
TRPA1 O75762 1/20 0.30
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5150512 0.86 GABRA1 (0.42) GABRA1GABRB2CASRTSHRTDP1
SCHEMBL12077605 0.79 KCNN4 (0.39) TSHRTDP1ALDH1A1ACHECTNNB1
SCHEMBL20005896 0.79 KCNN4 (0.39) TSHRTDP1ALDH1A1ACHECTNNB1
SCHEMBL372803 0.77 CNR2 (0.43)
SCHEMBL3815476 0.77 CNR2 (0.43)
SCHEMBL17800818 0.77 CNR2 (0.43)
SCHEMBL6900997 0.77 CNR2 (0.43)
SCHEMBL17800826 0.77 CNR2 (0.43)
Hydrochloric Acid SCHEMBL10760883 0.77 CNR2 (0.40) CASRTDP1L3MBTL1CYP3A4
SCHEMBL4667119 0.77 KIF11 (0.37) TSHRALDH1A1CYP3A4CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 92 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240026432-A1 POLYVINYL SULFONATE DETECTION AND REMOVAL FROM BIOMOLECULE COMPOSITIONS AMGEN INC. 2024-01-25 US claimed
EP-4229219-A2 POLYVINYL SULFONATE DETECTION AND REMOVAL FROM BIOMOLECULE COMPOSITIONS Amgen Inc. (US) 2023-08-23 EP claimed
CN-116368239-A Detection and removal of polyvinylsulfonates from biomolecular compositions 美国安进公司 2023-06-30 CN claimed
WO-2022081939-A2 POLYVINYL SULFONATE DETECTION AND REMOVAL FROM BIOMOLECULE COMPOSITIONS AMGEN INC. (US) 2022-04-21 WO claimed
US-12603190-B2 Purification process for the preparation of non-carrier added copper-64 CURIUM US LLC (US) 2026-04-14 US disclosed
US-20260074083-A1 PURIFICATION PROCESS FOR THE PREPARATION OF NON-CARRIER ADDED COPPER-64 CURIUM US LLC (US) 2026-03-12 US disclosed
US-20260074084-A1 PURIFICATION PROCESS FOR THE PREPARATION OF NON-CARRIER ADDED COPPER-64 CURIUM US LLC (US) 2026-03-12 US disclosed
WO-2026041748-A1 AROMATIC COMPOUNDS IN LOW CONDUCTIVE HEAT-TRANSFER FLUIDS Arteco N.v. (BE) 2026-02-26 WO disclosed
EP-4700099-A1 AROMATIC COMPOUNDS IN LOW CONDUCTIVE HEAT-TRANSFER FLUIDS Arteco NV (BE) 2026-02-25 EP disclosed
US-20260015743-A1 MEDIATED HYDROGEN ANODE FOR USE IN REDUCTIVE ELECTROSYNTHESIS WISCONSIN ALUMNI RES FOUND (US) 2026-01-15 US disclosed
US-20250368528-A1 COPPER-64 COMPOSITIONS AND PURIFICATION PROCESSES FOR THE PREPARATION OF NOVEL COPPER-64 COMPOSITIONS CURIUM US LLC (US) 2025-12-04 US disclosed
US-12462943-B2 Purification process for the preparation of non-carrier added copper-64 CURIUM US LLC (US) 2025-11-04 US disclosed
EP-1784885-A1 COLORANT TREATED ION EXCHANGE RESINS, METHOD OF MAKING, HEAT TRANSFER SYSTEMS AND ASSEMBLIES CONTAINING THE SAME, AND METHOD OF USE Honeywell International Inc. (US) 2007-05-16 EP disclosed
US-20070055055-A1 Protein separation from a protein mixture FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2007-03-08 US disclosed
US-20060205928-A1 Separation of albumin from protein samples FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2006-09-14 US disclosed
WO-2006096479-A2 PROTEIN SEPARATION FROM A PROTEIN MIXTURE FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2006-09-14 WO disclosed
US-20060063050-A1 Colorant treated ion exchange resins, method of making, heat transfer systems and assemblies containing the same, and method of use GOLDMAN SACHS MIDDLE MARKET LENDING CORP. II 2006-03-23 US disclosed
WO-2006029327-A2 TREATED ION EXCHANGE RESINS, METHOD OF MAKING, ASSEMBLIES AND HEAT TRANSFER SYSTEMS CONTAINING THE SAME, AND METHOD OF USE HONEYWELL INTERNATIONAL INC. (US) 2006-03-16 WO disclosed
WO-2006029178-A1 COLORANT TREATED ION EXCHANGE RESINS, METHOD OF MAKING, HEAT TRANSFER SYSTEMS AND ASSEMBLIES CONTAINING THE SAME, AND METHOD OF USE HONEYWELL INTERNATIONAL INC. (US) 2006-03-16 WO disclosed
US-20060049167-A1 Treated ion exchange resins, method of making, assemblies and heat transfer systems containing the same, and method of use GOLDMAN SACHS MIDDLE MARKET LENDING CORP. II 2006-03-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260074083-A1 PURIFICATION PROCESS FOR THE PREPARATION OF NON-CARRIER ADDED COPPER-64 SLC39A14, SLC39A3, SLC39A7 GABRA1 2959/4885GABRB2 2570/4885CASR 1180/4885
US-20260015743-A1 MEDIATED HYDROGEN ANODE FOR USE IN REDUCTIVE ELECTROSYNTHESIS HAO2, HACL2, HVCN1 GABRA1 953/4885GABRB2 898/4885CASR 1722/4885
US-20260074084-A1 PURIFICATION PROCESS FOR THE PREPARATION OF NON-CARRIER ADDED COPPER-64 SLC39A14, MAX, SLC7A1 GABRA1 1677/4885GABRB2 1759/4885CASR 394/4885
US-12603190-B2 Purification process for the preparation of non-carrier added copper-64 SLC39A14, SLC39A3, SLC39A7 GABRA1 3563/4885GABRB2 3254/4885CASR 1472/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.