Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 7/20 | 0.59 |
| ▸ | MMP3 | P08254 | 1/20 | 0.59 |
| ▸ | STS | P08842 | 1/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | CA3 | P07451 | 1/20 | 0.54 |
| ▸ | CA6 | P23280 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.54 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.49 |
| ▸ | ESR1 | P03372 | 6/20 | 0.44 |
| ▸ | AR | P10275 | 2/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | ESRRB | O95718 | 1/20 | 0.41 |
| ▸ | ESRRA | P11474 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18406709 | 0.81 | STS (0.55) | STSARKDM1AMAOA | |
| SCHEMBL5633361 | 0.81 | STS (0.54) | ESR2STSCYP19A1MAOA | |
| SCHEMBL15420921 | 0.80 | ESR2 (0.58) | ESR2MMP3CYP19A1ESR1AR | |
| SCHEMBL28165919 | 0.80 | MMP3 (0.57) | ESR2MMP3CA12CA2CA3 | |
| SCHEMBL18664451 | 0.80 | MMP3 (0.57) | ESR2MMP3CA12CA2CA3 | |
| SCHEMBL2786090 | 0.80 | MMP3 (0.57) | ESR2MMP3CA12CA2CA3 | |
| SCHEMBL25418472 | 0.80 | STS (0.50) | STSCA12CA2CA3CA6 | |
| SCHEMBL2751685 | 0.79 | STS (0.53) | ESR2MMP3STSCYP19A1KDM1A | |
| SCHEMBL6068004 | 0.77 | MMP3 (0.63) | ESR2MMP3CA12CA2CA3 | |
| SCHEMBL9955106 | 0.76 | MMP3 (0.57) | ESR2MMP3CA12CA2CA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1193250-B1 | PHENYL SULFAMATE DERIVATIVES | TEIKOKU HORMONE MFG CO LTD (JP) | 2008-06-04 | — | — | EP | disclosed |
| US-6762205-B1 | STEROID SULFATASE INHIBITORS WITHOUT ESTROGENIC SIDE EFFECT ACTION | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 2004-07-13 | — | — | US | disclosed |
| EP-1193250-A1 | PHENYL SULFAMATE DERIVATIVES | Teikoku Hormone Mfg. Co., Ltd. (JP) | 2002-04-03 | — | — | EP | disclosed |