Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 1/20 | 0.53 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.35 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.35 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | CHKA | P35790 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2753702 | 0.85 | STS (0.39) | STSIMPDH2IMPDH1ESR2CYP19A1 | |
| SCHEMBL5633361 | 0.82 | STS (0.54) | STSESR2CYP19A1PTGDR2MAOA | |
| SCHEMBL25418472 | 0.81 | STS (0.50) | STSIMPDH2IMPDH1CYP11B1CYP11B2 | |
| SCHEMBL2751214 | 0.80 | STS (0.43) | STSESR2PRMT5WDR77CYP19A1 | |
| SCHEMBL9019577 | 0.79 | KDM4E (0.44) | STSESR2CYP19A1CHKA | |
| SCHEMBL4667162 | 0.79 | ESR2 (0.59) | STSESR2CYP19A1KDM1AMAOA | |
| SCHEMBL18406709 | 0.79 | STS (0.55) | STSKDM1AMAOACYP11B2 | |
| SCHEMBL2754405 | 0.79 | STS (0.44) | STSPRMT5WDR77CYP19A1PTGDR2 | |
| SCHEMBL28232459 | 0.76 | VCAM1 (0.32) | STSMMP3CYP11B1CYP11B2 | |
| SCHEMBL18411429 | 0.74 | STS (0.47) | STSESR2CYP19A1PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101541764-B | Pyrimidylmethyl-sulfonamide compounds useful as fungicides and against arthropods | BASF SE | 2012-10-10 | — | — | CN | disclosed |
| US-8178540-B2 | Pyrimidylmethyl-sulfonamide compounds | BASF SE (DE) | 2012-05-15 | — | — | US | disclosed |
| US-20100077512-A1 | Pyridazin-4-ylmethyl-sulfonamides used as Fungicides and Against Arthropods | BASF SE (DE) | 2010-03-25 | — | — | US | disclosed |
| US-20100069243-A1 | Pyrimidylmethyl-Sulfonamide Compounds | BASF SE (DE) | 2010-03-18 | — | — | US | disclosed |
| CN-101541764-A | Pyrimidylmethyl-sulfonamide compounds useful as fungicides and against arthropods | BASF SE (DE) | 2009-09-23 | — | — | CN | disclosed |
| CN-101541762-A | Pyridazin-4-ylmethyl-sulfonamide compounds as fungicides and against arthropods | BASF SE (DE) | 2009-09-23 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100069243-A1 | Pyrimidylmethyl-Sulfonamide Compounds | TPMT, NISCH, PPA1 | STS 10/4885IMPDH2 113/4885IMPDH1 144/4885 |
| US-20100077512-A1 | Pyridazin-4-ylmethyl-sulfonamides used as Fungicides and Against Arthropods | PIR, PRDX4, PRDX2 | STS 6/4885IMPDH2 1488/4885IMPDH1 1870/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.