Formic Acid

Formic Acid

SCHEMBL4667355

Cc1ccc(S(=O)(=O)Nc2ccc(Nc3cc(-c4ccc5c(ccn5CC(C)N5CCN(C)CC5)c4)ncn3)cc2)c(F)c1.O=CO

nearest known ligand 0.34

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ABL1 P00519 6/20 0.34
BCR P11274 6/20 0.34
PRMT5 O14744 1/20 0.33
WDR77 Q9BQA1 1/20 0.33
PRF1 P14222 1/20 0.33
RPS6KA3 P51812 1/20 0.33
RORC P51449 1/20 0.33
CDK4 P11802 3/20 0.33
CDK1 P06493 2/20 0.32
CDK6 Q00534 1/20 0.32
SGK1 O00141 2/20 0.32
KIT P10721 1/20 0.32
CCNB1 P14635 1/20 0.32
CCNE1 P24864 1/20 0.32
BPTF Q12830 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Formic Acid SCHEMBL4667465 0.95 ABL1 (0.34) ABL1BCRPRF1RORCCDK4
Formic Acid SCHEMBL4665681 0.90 HTR7 (0.37) ABL1BCRPRF1RPS6KA3RORC
Formic Acid SCHEMBL4663906 0.88 KDM1A (0.35) ABL1BCRPRF1RORCCDK4
Formic Acid SCHEMBL4663848 0.87 RORC (0.35) ABL1BCRPRF1RORCCDK4
SCHEMBL4667361 0.87 MEN1 (0.32) ABL1BCRPRMT5WDR77RPS6KA3
Formic Acid SCHEMBL4664032 0.87 HTR6 (0.39) ABL1BCRPRF1RORCKIT
Formic Acid SCHEMBL4664389 0.86 RORC (0.34) ABL1BCRPRF1RORCCDK4
Formic Acid SCHEMBL4666201 0.85 BPTF (0.46) BPTF
Formic Acid SCHEMBL4663890 0.85 PRF1 (0.45) ABL1BCRPRF1RORCSGK1
Formic Acid SCHEMBL4665663 0.84 HTR6 (0.45) ABL1BCRPRF1RORCBPTF

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080242681-A1 N-4-(6-(Hetero)Aryl-Pyrimidin-4-Ylaminophenyl)-Benzenesulfonamides as Kinase Inhibitors ALTANA PHARMA AG (DE) 2008-10-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080242681-A1 N-4-(6-(Hetero)Aryl-Pyrimidin-4-Ylaminophenyl)-Benzenesulfonamides as Kinase Inhibitors MAP3K19, MAP3K6, MAP3K20 ABL1 24/4885BCR 402/4885PRMT5 504/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.