Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 2/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.35 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.35 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | PRKDC | P78527 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30639142 | 0.81 | RAD52 (0.45) | FTOKDM4CKDM5BKDM2AKDM3A | |
| SCHEMBL23770974 | 0.79 | MEN1 (0.47) | SCN9AKCNH2SCN5AKDRMEN1 | |
| SCHEMBL29527700 | 0.79 | RAD52 (0.48) | FTOKDM4CKDM5BKDM2AKDM3A | |
| SCHEMBL6120458 | 0.79 | RAD52 (0.48) | FTOKDM4CKDM5BKDM2AKDM3A | |
| SCHEMBL4667858 | 0.79 | KDM4E (0.53) | KDRABL1AURKAPIK3CAPRKDC | |
| SCHEMBL20796132 | 0.78 | FTO (0.46) | FTOKDM4CKDM5BKDM2AKDM3A | |
| SCHEMBL30202244 | 0.78 | FTO (0.46) | FTOKDM4CKDM5BKDM2AKDM3A | |
| SCHEMBL23999755 | 0.78 | RAD52 (0.59) | KDRFTOKDM4CKDM5BKDM2A | |
| SCHEMBL4667856 | 0.77 | SCN9A (0.63) | SCN9AKCNH2SCN5ARAD52MEN1 | |
| SCHEMBL913981 | 0.76 | HCAR3 (0.56) | HCAR3MEN1LMNAKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1982749-B1 | Novel hair colouring compositions for use in oxidative hair dyeing | PROCTER & GAMBLE (US) | 2013-04-17 | — | — | EP | claimed |
| EP-1982749-A2 | Novel hair colouring compositions for use in oxidative hair dyeing | The Procter and Gamble Company (US) | 2008-10-22 | — | — | EP | claimed |
| US-7303592-B2 | Hair coloring compositions for use in oxidative hair dyeing | THE PROCTER & GAMBLE COMPANY (US) | 2007-12-04 | — | — | US | claimed |
| EP-1855644-A2 | HAIR COLORING COMPOSITIONS FOR USE IN OXIDATIVE HAIR DYEING | The Procter and Gamble Company (US) | 2007-11-21 | — | — | EP | claimed |
| WO-2006099115-A2 | HAIR COLORING COMPOSITIONS FOR USE IN OXIDATIVE HAIR DYEING | THE PROCTER & GAMBLE COMPANY (US) | 2006-09-21 | — | — | WO | claimed |
| US-20050188480-A1 | Novel hair coloring compositions for use in oxidative hair dyeing | WELLA OPERATIONS US, LLC | 2005-09-01 | — | — | US | claimed |
| EP-1982749-B1 | Novel hair colouring compositions for use in oxidative hair dyeing | PROCTER & GAMBLE (US) | 2013-04-17 | — | — | EP | disclosed |
| EP-1982749-A2 | Novel hair colouring compositions for use in oxidative hair dyeing | The Procter and Gamble Company (US) | 2008-10-22 | — | — | EP | disclosed |
| EP-1982748-A2 | Novel hair colouring compositions for use in oxidative hair dyeing | The Procter & Gamble (US) | 2008-10-22 | — | — | EP | disclosed |
| US-7303592-B2 | Hair coloring compositions for use in oxidative hair dyeing | THE PROCTER & GAMBLE COMPANY (US) | 2007-12-04 | — | — | US | disclosed |
| EP-1855644-A2 | HAIR COLORING COMPOSITIONS FOR USE IN OXIDATIVE HAIR DYEING | The Procter and Gamble Company (US) | 2007-11-21 | — | — | EP | disclosed |
| WO-2006099115-A2 | HAIR COLORING COMPOSITIONS FOR USE IN OXIDATIVE HAIR DYEING | THE PROCTER & GAMBLE COMPANY (US) | 2006-09-21 | — | — | WO | disclosed |
| US-20050188480-A1 | Novel hair coloring compositions for use in oxidative hair dyeing | WELLA OPERATIONS US, LLC | 2005-09-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050188480-A1 | Novel hair coloring compositions for use in oxidative hair dyeing | COXFA4L2, TYR, GPX4 | SCN9A 1395/4885KCNH2 1434/4885SCN5A 435/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.