SCHEMBL4667786

SCHEMBL4667786

CC(=O)NCc1cc(C(C)=NOCc2cccc(C)n2)ccc1Cl

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.40
NPC1 O15118 2/20 0.39
RAB9A P51151 2/20 0.39
PPARG P37231 3/20 0.38
PPARA Q07869 3/20 0.38
L3MBTL1 Q9Y468 1/20 0.37
PTGES O14684 1/20 0.36
ADORA2A P29274 1/20 0.36
DPP4 P27487 1/20 0.36
NQO2 P16083 1/20 0.36
BDKRB2 P30411 1/20 0.35
HPGD P15428 1/20 0.35
IRAK4 Q9NWZ3 1/20 0.35
BRD4 O60885 1/20 0.35
BRD2 P25440 1/20 0.35
BRD3 Q15059 1/20 0.35
BRDT Q58F21 1/20 0.35
MEN1 O00255 1/20 0.34
OPRM1 P35372 1/20 0.34
OPRD1 P41143 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4667781 1.00 NPSR1 (0.40) NPSR1NPC1RAB9APPARGPPARA
SCHEMBL2778024 0.94 NPC1 (0.41) NPC1RAB9APPARGPPARAPTGES
SCHEMBL2744757 0.94 NPC1 (0.41) NPC1RAB9APPARGPPARAPTGES
SCHEMBL2744761 0.94 NPC1 (0.41) NPC1RAB9APPARGPPARAPTGES
Pyribencarb SCHEMBL18875 0.93 NPC1 (0.39) NPC1RAB9APPARGPPARAPTGES
Pyribencarb SCHEMBL557610 0.93 NPC1 (0.39) NPC1RAB9APPARGPPARAPTGES
Pyribencarb SCHEMBL29935941 0.93 NPC1 (0.39) NPC1RAB9APPARGPPARAPTGES
Pyribencarb SCHEMBL3228377 0.93 NPC1 (0.39) NPC1RAB9APPARGPPARAPTGES
Pyribencarb SCHEMBL557599 0.90 NPC1 (0.38) NPC1RAB9APPARGPPARAPTGES
SCHEMBL12855963 0.87 NPC1 (0.36) NPC1RAB9APPARGPPARAPTGES

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1980150-A1 Fungicidal mixtures based on triazolopyrimidine compounds BASF SE (DE) 2008-10-15 EP disclosed