SCHEMBL2744757

SCHEMBL2744757

C/C(=N/OCc1cccc(C)n1)c1ccc(Cl)c(CNC(=O)O)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.41
RAB9A P51151 2/20 0.41
PPARG P37231 6/20 0.40
PPARA Q07869 4/20 0.40
MEN1 O00255 1/20 0.39
OPRM1 P35372 1/20 0.39
OPRD1 P41143 1/20 0.39
KMT2A Q03164 1/20 0.39
HPGD P15428 1/20 0.37
PTGES O14684 1/20 0.36
ADORA2A P29274 1/20 0.36
DPP4 P27487 1/20 0.36
S1PR1 P21453 2/20 0.35
S1PR3 Q99500 1/20 0.35
PPARD Q03181 1/20 0.35
BRD4 O60885 1/20 0.35
BRD2 P25440 1/20 0.35
BRD3 Q15059 1/20 0.35
BRDT Q58F21 1/20 0.35
SORT1 Q99523 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2744761 1.00 NPC1 (0.41) NPC1RAB9APPARGPPARAMEN1
SCHEMBL2778024 1.00 NPC1 (0.41) NPC1RAB9APPARGPPARAMEN1
SCHEMBL4667781 0.94 NPSR1 (0.40) NPC1RAB9APPARGPPARAMEN1
SCHEMBL4667786 0.94 NPSR1 (0.40) NPC1RAB9APPARGPPARAMEN1
Pyribencarb SCHEMBL29935941 0.93 NPC1 (0.39) NPC1RAB9APPARGPPARAMEN1
Pyribencarb SCHEMBL3228377 0.93 NPC1 (0.39) NPC1RAB9APPARGPPARAMEN1
Pyribencarb SCHEMBL18875 0.93 NPC1 (0.39) NPC1RAB9APPARGPPARAMEN1
Pyribencarb SCHEMBL557610 0.93 NPC1 (0.39) NPC1RAB9APPARGPPARAMEN1
Pyribencarb SCHEMBL557599 0.92 NPC1 (0.38) NPC1RAB9APPARGPPARAMEN1
SCHEMBL12855963 0.87 NPC1 (0.36) NPC1RAB9APPARGPPARAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 472 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3954214-A1 MULTIPURPOSE BIOLOGICAL COMPOSITIONS Agrivalle Brasil Industria e Comércio de Produtos Agrícolas Ltda (BR) 2022-02-16 EP claimed
EP-3381289-B1 COMBINATIONS COMPRISING A FUNGICIDAL STRAIN AND AN ACTIVE COMPOUND BAYER CROPSCIENCE LP (US) 2021-05-05 EP claimed
US-10834921-B2 Foam formulations and apparatus for delivery FMC CORPORATION (US) 2020-11-17 US claimed
WO-2020206518-A1 MULTIPURPOSE BIOLOGICAL COMPOSITIONS AGRIVALLE BRASIL INDUSTRIA E COMÉRCIO DE PRODUTOS AGRÍCOLAS LTDA (BR) 2020-10-15 WO claimed
EP-2292098-B1 Combinations comprising a fungicidal strain and at least one additional fungicide BAYER CROPSCIENCE LP (US) 2019-11-06 EP claimed
EP-3381289-A1 COMBINATIONS COMPRISING A FUNGICIDAL STRAIN AND AN ACTIVE COMPOUND Bayer Cropscience LP (US) 2018-10-03 EP claimed
US-20180007908-A1 Pesticidal Mixtures BASF SE (DE) 2018-01-11 US claimed
US-20170318816-A1 Combinations Comprising a Fungicidal Strain and an Active Compound BAYER CROPSCIENCE LP 2017-11-09 US claimed
EP-3240421-A1 MICROBIAL COMPOSITIONS FOR USE IN COMBINATION WITH SOIL INSECTICIDES FOR BENEFITING PLANT GROWTH FMC Corporation (US) 2017-11-08 EP claimed
EP-3240406-A1 BACILLUS AMYLOLIQUEFACIENS RTI472 COMPOSITIONS AND METHODS OF USE FOR BENEFITING PLANT GROWTH AND TREATING PLANT DISEASE FMC CORPORATION (US) 2017-11-08 EP claimed
EP-1912504-A1 METHOD FOR CONTROLLING RUST INFECTIONS IN LEGUMINOUS PLANTS BASF SE (DE) 2008-04-23 EP claimed
WO-2008034787-A2 PESTICIDAL MIXTURES COMPRISING AN ANTHRANILAMIDE INSECTICIDE AND A FUNGICIDE BASF SE (DE) 2008-03-27 WO claimed
WO-2008034785-A2 PESTICIDAL MIXTURES COMPRISING AN ANTHRANILAMIDE INSECTICIDE AND A FUNGICIDE BASF SE (DE) 2008-03-27 WO claimed
US-20080076747-A1 Fungicidal Mixtures BASF AKTIENGESELLSCHAFT (DE) 2008-03-27 US claimed
US-20080045414-A1 Of 2,3-dimethyl-3-(3-pyridyl)-5-(4-chlorophenyl)isoxazolidine and at least one other fungicide; reduced application rate, broadened spectrum; synergistic against phytopathogens BASF AKTIENGESELLSCHAFT (DE) 2008-02-21 US claimed
WO-2007128756-A1 USE OF ARYLCARBOXYLIC ACID BIPHENYLAMIDES FOR SEED TREATMENT BASF SE (DE) 2007-11-15 WO claimed
WO-2007104660-A2 METHOD FOR IMPROVING THE TOLERANCE OF PLANTS TO CHILLING TEMPERATURES AND/OR FROST BASF SE (DE) 2007-09-20 WO claimed
WO-2007048735-A2 METHOD OF INDUCING RESISTANCE TO HARMFUL FUNGI BASF SE (DE) 2007-05-03 WO claimed
WO-2007017231-A1 USE OF ARYLANILIDES FOR SEED TREATMENT BASF AKTIENGESELLSCHAFT (DE) 2007-02-15 WO claimed
WO-2007017409-A1 METHOD FOR CONTROLLING RUST INFECTIONS IN LEGUMINOUS PLANTS BASF SE (DE) 2007-02-15 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080076747-A1 Fungicidal Mixtures ERG28, CYP51A1, CASP7 NPC1 1130/4885RAB9A 1167/4885PPARG 4236/4885
US-20180007908-A1 Pesticidal Mixtures PTMS, THOP1, MLN NPC1 4658/4885RAB9A 2723/4885PPARG 3064/4885
US-20170318816-A1 Combinations Comprising a Fungicidal Strain and an Active Compound O60361, SPOUT1, FBL NPC1 4012/4885RAB9A 3858/4885PPARG 1913/4885
US-20080045414-A1 Of 2,3-dimethyl-3-(3-pyridyl)-5-(4-chlorophenyl)isoxazolidine and at least one other fungicide; reduced application rate, broadened spectrum; synergistic against phytopathogens DDT, CYP4X1, STS NPC1 3820/4885RAB9A 3048/4885PPARG 1699/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.