Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 5/20 | 0.38 |
| ▸ | PPARA | Q07869 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | PTGES | O14684 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CD38 | P28907 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyribencarb SCHEMBL3228377 | 0.96 | NPC1 (0.39) | NPC1RAB9APPARGPPARAMEN1 | |
| Pyribencarb SCHEMBL18875 | 0.96 | NPC1 (0.39) | NPC1RAB9APPARGPPARAMEN1 | |
| Pyribencarb SCHEMBL29935941 | 0.96 | NPC1 (0.39) | NPC1RAB9APPARGPPARAMEN1 | |
| Pyribencarb SCHEMBL557610 | 0.96 | NPC1 (0.39) | NPC1RAB9APPARGPPARAMEN1 | |
| SCHEMBL2778024 | 0.92 | NPC1 (0.41) | NPC1RAB9APPARGPPARAMEN1 | |
| SCHEMBL2744761 | 0.92 | NPC1 (0.41) | NPC1RAB9APPARGPPARAMEN1 | |
| SCHEMBL2744757 | 0.92 | NPC1 (0.41) | NPC1RAB9APPARGPPARAMEN1 | |
| SCHEMBL4667786 | 0.90 | NPSR1 (0.40) | NPC1RAB9APPARGPPARAMEN1 | |
| SCHEMBL4667781 | 0.90 | NPSR1 (0.40) | NPC1RAB9APPARGPPARAMEN1 | |
| SCHEMBL4622925 | 0.88 | MEN1 (0.36) | NPC1RAB9APPARGPPARAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110166109-A1 | Synergistic Active Compound Combinations Comprising Phenyltriazoles | BAYER CROPSCIENCE AG (DE) | 2011-07-07 | — | — | US | claimed |
| US-9012360-B2 | Synergistic combinations of active ingredients | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-04-21 | — | — | US | disclosed |
| US-20120035050-A1 | Synergistic Combinations Of Active Ingredients | BAYER CROPSCIENCE AG (DE) | 2012-02-09 | — | — | US | disclosed |
| US-20110166109-A1 | Synergistic Active Compound Combinations Comprising Phenyltriazoles | BAYER CROPSCIENCE AG (DE) | 2011-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120035050-A1 | Synergistic Combinations Of Active Ingredients | C1S, MAN2B1, MANBA | NPC1 1026/4885RAB9A 513/4885PPARG 4292/4885 |
| US-20110166109-A1 | Synergistic Active Compound Combinations Comprising Phenyltriazoles | NAT1, ACAT1, CAT | NPC1 1734/4885RAB9A 3686/4885PPARG 1875/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.